grant
Research Programs
Organization JACKSON LABORATORYLocation BAR HARBOR, UNITED STATESPosted 1 Aug 1997Deadline 30 Jun 2030
NIHUS FederalResearch GrantFY2025AI basedAddressAdvanced CancerAdvanced Malignant NeoplasmAffectAgeAge related pathologiesAgingAnimal ModelAnimal Models and Related StudiesBasic ResearchBasic ScienceBiologyBiology of AgingBody TissuesCCSGCancer BiologyCancer CenterCancer Center Support GrantCancer TreatmentCancersCell AgingCell BodyCell FunctionCell PhysiologyCell ProcessCell SenescenceCell modelCellsCellular AgingCellular FunctionCellular PhysiologyCellular ProcessCellular SenescenceCellular biologyCellular modelCenter for Cancer ResearchChronicCirculatory CollapseClinicalCollaborationsComputer ModelsComputerized ModelsDNADNA DamageDNA InjuryDNA mutationDataDeoxyribonucleic AcidDevelopmentDifferences between sexesDiffers between sexesDimensionsDirect CostsDisease ResistanceDysfunctionEducational workshopEnvironmentEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessFaculty RecruitmentFosteringFoundationsFunctional disorderFundingFutureGene TranscriptionGeneticGenetic ChangeGenetic Models for CancerGenetic ResearchGenetic TranscriptionGenetic defectGenetic mutationGenomicsGoalsGrantHematopoiesisHematopoietic Cellular Control MechanismsHeterogeneityHormonal ChangeHost-Tumor InteractionHumanHuman BiologyImageImmuneImmune DiseasesImmune DisordersImmune DysfunctionImmune System DiseasesImmune System DisorderImmune System DysfunctionImmune System and Related DisordersImmune systemImmunesImmunologic DiseasesImmunological DiseasesImmunological DysfunctionImmunological System DysfunctionIn VitroIndividualInflammationInter-tumoral heterogeneityInterventionInvestigatorsJournalsLaboratoriesLeadershipLife CycleLife Cycle StagesMagazineMalignant CellMalignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorMedicineMetastasisMetastasizeMetastatic LesionMetastatic MassMetastatic NeoplasmMetastatic TumorMiceMice MammalsModelingModern ManModificationMurineMusMutationNCI Center for Cancer ResearchNCI-Designated Cancer CenterNamesNeoplasm MetastasisOncogenicOrganismOutcomePathologyPatientsPatternPeer ReviewPersonsPhenotypePhysiologyPhysiopathologyPreventiveProcessProgenitor CellsPublishingRNA ExpressionRNA SplicingReplicative SenescenceResearchResearch PersonnelResearch Project SummariesResearchersResource DevelopmentRiskRoleScholars ProgramSecondary NeoplasmSecondary TumorSeriesSex DifferencesSexual differencesShapesShockSplicingStudy modelsSubcellular ProcessSystemTechnologyTestingThe Jackson LaboratoryTherapeuticTimeTissuesTranscriptionTravelTumor TissueVertebrate AnimalsVertebratesWorkWorkshopage associated pathologiesage dependent pathologiesage induced pathologiesagedagesaging associatedaging associated pathologiesaging dependent pathologiesaging induced pathologiesaging pathologiesaging processaging relatedaging related pathologiesanti-cancer researchanti-cancer therapyartificial intelligence basedblood cell formationcancer cellcancer metastasiscancer microenvironmentcancer progressioncancer researchcancer statisticscancer therapycancer-directed therapycell biologycirculatory shockcomputational intelligencecomputational modelingcomputational modelscomputer based modelscomputerized modelingdesigndesigningdevelopmentaldisease riskdisorder riskempowermentepigeneticallygenome mutationhost neoplasm interactionimagingin silicoin vivoin vivo Modelinsightintertumoral heterogeneitylab assignmentlab experimentlaboratory activitylaboratory assignmentlaboratory exerciselaboratory experimentlife courseliving systemmalignancymeetingmeetingsmembermitochondrial dysfunctionmodel of animalnamenamednamingnatural agingneoplasm progressionneoplasm/cancerneoplastic progressionnormal agingnormative agingnovelpathophysiologypersonalized geneticspre-neoplastic cellprecision geneticspreneoplastic cellpreventpreventingprogramsrecruit teachersreplicative agingresistance to diseaseresistance to therapyresistant diseaseresistant to diseaseresistant to therapyresponseresponse to therapyresponse to treatmentsex based differencessex-dependent differencessex-related differencessex-specific differencesshockssocial rolespatial RNA sequencingspatial gene expression analysisspatial gene expression profilingspatial resolved transcriptome sequencingspatial transcriptome analysisspatial transcriptome profilingspatial transcriptome sequencingspatial transcriptomicsspatially resolved transcriptomicsspatio transcriptomicsstem cellssuccessteacher recruitmenttherapeutic resistancetherapeutic responsetherapy resistanttherapy responsetissue progenitortissue specific progenitor cellstissue specific stem cellstissue stem cellstreatment resistancetreatment responsetreatment responsivenesstumortumor cell metastasistumor microenvironmenttumor progressionvertebrata
Description preview
PROJECT SUMMARY RESEARCH PROGRAM
The overarching goal of The Jackson Laboratory Cancer Center (JAXCC) Research Program, “Genetics and
Genomics of Aging and Cancer”, is to advance cancer medicine through basic research discoveries with
potential for preventive and therapeutic impact for patients. Our Research Program is focused on uncovering…
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