grant
Relapse after Discontinuation of Antipsychotics during Pregnancy (R-DAP study)
Organization ICAHN SCHOOL OF MEDICINE AT MOUNT SINAILocation NEW YORK, UNITED STATESPosted 2 Mar 2020Deadline 31 Jan 2029
NIHUS FederalResearch GrantFY20250-11 years oldActive Follow-upAffective DisordersAntipsychotic AgentsAntipsychotic DrugsAntipsychoticsBenefits and RisksBipolar Affective PsychosisBipolar DisorderBirth WeightChildChild YouthChildren (0-21)Chronologic Fetal MaturityClinical ResearchClinical StudyControl GroupsDataDenmarkDeveloping fetusDiseaseDisorderDrugsExposure toFamilyFathersFetal AgeFetal DevelopmentFetusGestationGestational AgeHealthHigh Risk WomanHospital AdmissionHospitalizationInfanticideInpatientsKnowledgeLamictalLamiktalLi+ elementLithiumLong-Term EffectsMajor TranquilizersMajor Tranquilizing AgentsManic-Depressive PsychosisMaternal HealthMaternal MortalityMedicationMental HealthMental HygieneMeta-AnalysisMetabolicMetabolic DiseasesMetabolic DisorderMonitorMood DisordersMothersNeonatalNeuroleptic AgentsNeuroleptic DrugsNeurolepticsOutcomePatientsPerinatalPeripartumPharmaceutical PreparationsPopulationPostpartum PeriodPregnancyPregnant WomenPsychological HealthRecurrenceRecurrentRelapseResearch ResourcesResourcesRiskSample SizeSiblingsSourceSuicideSuicide attemptSwedenThesaurismosisTitrationsUnipolar DepressionWeight GainWeight IncreaseWomanactive comparatoractive comparison controlactive followupanti-depressant agentanti-depressant drugsanti-depressantsanti-depressive agentsat-risk femalesat-risk womenbefore conceptionbipolar affective disorderbipolar diseasebipolar illnessbipolar mood disorderbipolar patientsbipolar spectrumbody weight gainbody weight increasechildbearing agedrug/agentearly in pregnancyearly pregnanciesearly pregnancyearly stage of pregnancyexpectant motherexpectant womenexpecting motherexpecting womenexposed in uterofatal attemptfatal suicidefemales at high riskfertile agefetal exposurefollow upfollow-upfollowed upfollowuphealth of the motherhigh riskhigh risk femalesin uteroin utero exposureindividuals who are pregnantintent to dieintra-uterine environmental exposureintrauterine environmental exposurekidslamotriginemanic depressive disordermanic depressive illnessmaternal deathmaternal morbiditymetabolism disorderneonatal outcomenon fatal attemptnonfatal attemptnoveloffspringpeople who are pregnantperinatal periodperinatal phaseperinatal womenpopulation basedpost-partumpreconceptionpregnant femalespregnant motherspregnant peoplepregnant populationsprenatalprenatal exposureprenatally exposedpreventprevent relapsepreventingprior to conceptionrelapse preventionrelapse riskreproductive agereproductive yearssuicidal attemptsuicidal risksuicide risksuicidesthose who are pregnantunbornwomen at high riskwomen who are pregnantwt gainyoungster
Description preview
Project Summary
There is an increase in psychotropic medication use in women in their fertile ages. Due to concerns for the
developing fetus, half of women decide to discontinue their medication before- or at the beginning of pregnancy.
While the wish to avoid in utero medication exposure to the fetus is understandable, discontinuation of…
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