grant
Rare genitourinary tumors projects
Organization DIVISION OF BASIC SCIENCES - NCILocation UNITED STATES
NIHUS FederalResearch GrantFY2025AdenocarcinomaAdnexa CarcinomaAdnexal CarcinomaAffectBellini Duct CarcinomaBladderBladder AdenocarcinomaBladder CancerBladder CarcinomaBladder Epidermoid CarcinomaBladder Squamous Cell CarcinomaBladder Urinary SystemCancersCarcinomaCaringCell BodyCellsClinicalClinical ResearchClinical StudyClinical TrialsCollecting Duct CarcinomaCollecting Duct Type Renal Cell CarcinomaCollecting Ducts of Bellini CarcinomaCountryDNA mutationDataData PoolingDiseaseDisorderDrugsDuctDuct (organ) structureEpidermoid CarcinomaEpithelial cancerGenetic ChangeGenetic defectGenetic mutationGenitourinaryGenitourinary CancersGenitourinary systemHistologicHistologicallyHistologyHumanImmuneImmunesIncidenceIndividualKidney CancerKidney CarcinomaKidney Collecting Duct CarcinomaLaser ElectromagneticLaser RadiationLasersLiteratureMalignant AdenomaMalignant Bladder NeoplasmMalignant Epithelial NeoplasmsMalignant Epithelial TumorsMalignant NeoplasmsMalignant Penile TumorMalignant Testicular NeoplasmMalignant Testicular TumorMalignant TumorMalignant Tumor of the BladderMalignant Tumor of the TestisMalignant neoplasm of penisMalignant neoplasm of testisMalignant neoplasm of urinary bladderMedicationModern ManMutationNational Institutes of HealthNeuroendocrine NeoplasmNeuroendocrine TumorsNivolumabOpdivoOrphan DiseasePBMCPatientsPenile CancerPenile carcinomaPeripheral Blood Mononuclear CellPersonsPharmaceutical PreparationsPhasePhase I StudyPlanocellular CarcinomaRNA SeqRNA sequencingRNAseqRare DiseasesRare DisorderRenal CancerRenal CarcinomaRenal Collecting Duct CarcinomaRenal Medullary CarcinomaResearch ResourcesResourcesScienceSkin Appendage CarcinomaSmall Cell CancerSmall Cell CarcinomaSquamous CarcinomaSquamous Cell EpitheliomaSquamous cell carcinomaTesticular CancerTestis CancerTransitional CarcinomaTransitional Cell CarcinomaTumor ExpansionUnited States National Institutes of HealthUrethraUrinary Bladder AdenocarcinomaUrinary Bladder CancerUrinary Bladder CarcinomaUrinary Bladder Epidermoid CarcinomaUrinary Bladder Malignant TumorUrinary Bladder Squamous Cell CarcinomaUrogenitalUrogenital CancerUrogenital SystemUrothelial CarcinomaVariantVariationYervoybonecancer typecancers that are rarecohortdrug/agentepithelial carcinomaexome sequencingexome-seqgenitourinary tractgenome mutationipilimumabmalignancyneoplasm/cancerorphan disorderpenisphase 1 studyphase 2 studyphase II studyrare cancerrare malignancyrare tumorrecruitresponsetranscriptome sequencingtranscriptomic sequencingtumorurethralurinary bladderurogenital tract
Description preview
1. ICONIC-A phase 2 study of Ipilimumab, CabOzantinib, and NIvolumab in rare genitourinary (GU) cancers (ICONIC) The phase 1 study of combination CaboNivo and CaboNivoIpi included patients with rare GU histologies. Objective responses were seen in patients with adenocarcinoma of the bladder/urachal, squamous cell carcinoma of the bladder, small…
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