grant
Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer
Organization UNIVERSITY OF COLORADOLocation Boulder, UNITED STATESPosted 1 Aug 2025Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY20252-arm trial21+ years oldActive Follow-upAddressAdultAdult HumanAdvanced CancerAdvanced Malignant NeoplasmAdverse ExperienceAdverse eventAnxietyBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioral Conditioning TherapyBehavioral ModificationBehavioral TherapyBehavioral TreatmentCancer PatientCancer SurvivorCancersCannot see a futureCaringCausalityChinaClinicCognition TherapyCognitive PsychotherapyCognitive TherapyCognitive treatmentCommunitiesConditioning TherapyDiagnosisDisease ProgressionDissemination and ImplementationDistressEtiologyEvaluationEventFatigueFearFeelingFeeling hopelessFeels there is no futureFoundationsFrightFutureGeneral PopulationGeneral PublicGoalsGuidelinesHematopoietic Cell TumorHematopoietic MalignanciesHematopoietic NeoplasmsHematopoietic Neoplasms including LymphomasHematopoietic TumorHematopoietic and Lymphoid Cell NeoplasmHematopoietic and Lymphoid NeoplasmsImageInterventionKnowledgeLack of EnergyLoss of hope for the futureMainland ChinaMaintenanceMalignant Hematopoietic NeoplasmMalignant NeoplasmsMalignant TumorMediatingMental DepressionModelingNamesNational Institutes of HealthNegative about the futureNo hope for the futureOutcomeOverutilization of Health ServicesPatientsPopulationPrevalenceProcessPublishingQOLQuality of lifeRandomization trialRandomizedRecurrenceRecurrentRegretsReportingSafetySolidSolid NeoplasmSolid TumorSpanish/EnglishSpecific qualifier valueSpecifiedSymptom BurdenSymptomsTestingThinkingTimeTraumaUncertaintyUnited StatesUnited States National Institutes of HealthWorkWritingactive followupadulthoodalleviate symptomameliorating symptomanxiety reductionanxiousbehavior interventionbehavioral interventionblood cancercancer of bloodcancer of the bloodcancer progressioncare as usualcausationcognitive behavior interventioncognitive behavior modificationcognitive behavior therapycognitive behavioral interventioncognitive behavioral modificationcognitive behavioral therapycognitive behavioral treatmentcopingdecrease symptomdepressiondevelop therapydisease causationdoubteffective therapyeffective treatmentevidence basefeelingsfewer symptomsfollow upfollow-upfollowed upfollowuphealth care overutilizationhigh riskhopelessnessimagingimprovedindividualized cancer careindividualized oncologyintervention developmentmalignancynamenamednamingneoplasm progressionneoplasm/cancerneoplastic progressionnew approachesnovelnovel approachesnovel strategiesnovel strategyoveruse of health carepersonalized oncologyphysical symptompilot trialpost interventionpost-traumatic stress symptomspost-traumatic symptomsposttraumatic stress symptomsposttraumatic symptomsprecision cancer careprecision cancer medicineprecision oncologyprimary outcomeracial diversityracially diverserandomisationrandomizationrandomized trialrandomized, clinical trialsrandomly assignedrecruitreduce symptomsrelieves symptomsrural patientssecondary outcomesymptom alleviationsymptom reductionsymptom relieftelehealththeoriestherapy developmentthoughtstrauma symptomtreatment as usualtreatment developmenttumor progressiontwo-arm trialusual care
Description preview
ABSTRACT
Precision oncology has led to a growing population of adults with advanced cancer living increasingly longer
lives in the face of profound uncertainty about the future, with over half reporting moderate to high fear of cancer
progression (FoP)—anxiety about the high risk or certainty of disease progression. These fears are associated
with…
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