grant
Radiomics for Clinically-Acquired Brain MRIs of Youth with Neurodevelopmental Disorders
Organization CHILDREN'S HOSP OF PHILADELPHIALocation PHILADELPHIA, UNITED STATESPosted 8 Jul 2024Deadline 31 May 2029
NIHUS FederalResearch GrantFY20250-11 years oldASDAgeAnatomic SitesAnatomic structuresAnatomyAutismAutistic DisorderBenchmarkingBest Practice AnalysisBrainBrain Nervous SystemBrain imagingBrain regionBrain scanCaringCephalalgiaCephalgiaCephalodyniaChildChild YouthChildhoodChildren (0-21)Children's HospitalClinicalComplement Factor PComputer ModelsComputerized ModelsCopy Number PolymorphismCranial PainCraniocerebral InjuriesCraniocerebral TraumaDataData SetDevelopmentEarly Infantile AutismElectronic Health RecordEncephalonEnsureEnvironmental ExposureFutureGeneral RadiologyGeneralized GrowthGenesGeneticGenetic RiskGrowthHIPAAHead InjuriesHead PainHead TraumaHeadacheHealth Insurance Portability and Accountability ActHealth systemHospitalsIRBIRBsImageIndividualInfantile AutismInfrastructureInstitutional Review BoardsInvestigationInvestigatorsKanner's SyndromeKennedy Kassebaum ActMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMapsMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMethodologyModelingMolecularNMR ImagingNMR TomographyNatureNeural DevelopmentNeuranatomiesNeuranatomyNeuroanatomiesNeuroanatomyNeurodevelopmental DisorderNeurological Development DisorderNuclear Magnetic Resonance ImagingOutcomePL 104-191PL104-191ParticipantPathologyPathway interactionsPatternPediatric HospitalsPhenotypePhiladelphiaPopulationProbabilistic ModelsProbability ModelsProceduresProperdinProtocolProtocols documentationPsychiatryPsychopathologyPsychosesPublic Law 104-191Quality ControlRadiologyRadiology SpecialtyRainRecommendationRecordsReproducibilityResearchResearch PersonnelResearch ResourcesResearchersResource SharingResourcesRisk-associated variantSNP arraySNP chipSample SizeSamplingScanningScienceSiteStatistical ModelsStructureSymptomsTestingTissue GrowthTraumaUnited States Health Insurance Portability and Accountability ActVariantVariationWorkYouthYouth 10-21Zeugmatographyabnormal psychologyagesautism spectral disorderautism spectrum disorderautistic spectrum disorderbehavior phenotypebehavioral healthbehavioral phenotypingbenchmarkbiobankbiorepositorybrain MR imagingbrain MRIbrain magnetic resonance imagingbrain morphologybrain visualizationbrain volumecerebral MR imagingcerebral MRIcerebral magnetic resonance imagingcohortcommunity researchcompare to controlcomparison controlcomputational modelingcomputational modelscomputer based modelscomputerized modelingcopy number variantcopy number variationdeep learningdeep learning methoddeep learning strategydevelopmentalelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordfactor Phead achehigh riskimage processingimagingimaging Segmentationimaging geneticsindividual patientinterestkidslow-frequency mutationneural imagingneuro-imagingneurodevelopmentneurodevelopmental diseaseneurogenomicsneuroimagingneuroinformaticsneurological imagingneuropsychiatricneuropsychiatric diseaseneuropsychiatric disorderneuropsychiatryontogenypathwaypatient privacypediatricpolygenetic risk scorespolygenic risk scoreprospectiveradiomicsrainfallrare allelerare mutationrare variantrecruitresearch studyrisk allelerisk generisk genotyperisk locirisk locusrisk variantsecondary analysissingle nucleotide polymorphism arraysingle nucleotide polymorphism chipstatistical linear mixed modelsstatistical linear modelstooltrendyoungsteryouth age
Description preview
PROJECT ABSTRACT
The millions of brain MRIs acquired each year in clinical settings are a vastly underutilized scientific resource.
Meanwhile, brain MRIs collected in research studies often struggle to recruit cohorts fully representative of
populations of interest, particularly in the case of rare neurodevelopmental disorders. One clear…
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