grant
Project 2
Organization WAYNE STATE UNIVERSITYLocation DETROIT, UNITED STATESPosted 13 Feb 2024Deadline 31 Jan 2030
NIHUS FederalResearch GrantFY2026AddressAfrican AmericanAfrican American groupAfrican American individualAfrican American peopleAfrican American populationAfrican AmericansAfro AmericanAfroamericanAlcohol DrinkingAlcohol consumptionBaseline SurveysBiologic FactorBiological FactorsBloodBlood Reticuloendothelial SystemBreast CancerCancer BurdenCancer SurvivorCancer Susceptibility GeneCancer-Predisposing GeneCancersCessation of lifeCharacteristicsColorectal CancerConsentDNADNA SequenceDNA mutationDNA seqDNA sequencingDNAseqDataDeathDeath RateDeoxyribonucleic AcidDetectionDevelopmentDiagnosisEarly DiagnosisEndometrial CancerEndometrial CarcinomaEndometrium CancerEndometrium CarcinomaEnrollmentEnvironmental FactorEnvironmental Risk FactorEtOH drinkingEtOH useFaceFemale Breast CancerFemale Breast CarcinomaFrequenciesFutureGene variantGeneral PopulationGeneral PublicGenesGeneticGenetic ChangeGenetic DiversityGenetic PredispositionGenetic Predisposition to DiseaseGenetic SusceptibilityGenetic VariationGenetic defectGenetic mutationGenetic propensityGenetic studyGenomeGenotypeGerm LinesHereditaryIncidenceInfrastructureInheritedInherited PredispositionInherited SusceptibilityInvestigationKnowledgeMalignant Breast NeoplasmMalignant NeoplasmsMalignant TumorMalignant Tumor of the LungMalignant neoplasm of lungMalignant neoplasm of prostateMalignant prostatic tumorMammary Carcinoma of the Female BreastMedicalMedical RecordsMorbidityMutationNational Cancer BurdenNon-HispanicNonhispanicNot Hispanic or LatinoObesityOutcomeParticipantPathogenicityPhenotypePopulationPredisposition genePrevalencePreventionProstateProstate CAProstate CancerProstate GlandProstate malignancyProstatic GlandPulmonary CancerPulmonary malignant NeoplasmRaceRacesResearchResearch SpecimenRiskRisk FactorsRoleSNP arraySNP chipSalivaSecond CancerSecond Primary CancersSecondary MalignancySecondary Malignant NeoplasmSmokingSpecimenSurvey InstrumentSurveysSurvivorsSusceptibility GeneTestingTumor TissueUpdateVariantVariationWhole Bloodadiposityalcohol ingestionalcohol intakealcohol product usealcohol usealcoholic beverage consumptionalcoholic drink intakeallelic variantbreast cancer survivalcancer diagnosiscancer geneticscancer locationcancer predispositioncancer riskcancer sitecancer typeco-morbidco-morbiditycohortcomorbiditycorpulencedesigndesigningdevelopmentaldifferences due to racedifferences in racediffers by racediffers in raceearly detectionenrollentire genomeenvironmental riskethanol consumptionethanol drinkingethanol ingestionethanol intakeethanol product useethanol useexome sequencingexome-seqexperiencefacesfacialfull genomegenetic variantgenetic vulnerabilitygenetically predisposedgenome mutationgenome scalegenome-widegenomewidegenomic varianthigh risk grouphigh risk individualhigh risk peoplehigh risk populationimprovedlow-frequency mutationlung cancermalignancymalignant breast tumormortalitymortality ratemulti-ethnicmultiethnicneoplasm/cancernon-geneticnongeneticnovelpolygenetic risk scorespolygenic risk scorepredisposing generace based differencesrace differencesrace related differencesracialracial backgroundracial differenceracial originracially differentrare allelerare mutationrare variantresponserisk mitigationscreeningscreeningssecondary cancersingle nucleotide polymorphism arraysingle nucleotide polymorphism chipsocial rolesusceptibility allelesusceptibility locussusceptibility varianttumorwhole genome
Description preview
Project Summary
Survival for breast, prostate and colorectal cancer has improved dramatically over the past three decades as a result of advances in treatment and screening for the detection of these common cancers at an earlier stage. However, African Americans (AAs) still suffer from a higher mortality rate after diagnosis of these cancers…
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