grant
Project 2
Organization WAYNE STATE UNIVERSITYLocation DETROIT, UNITED STATESPosted 13 Feb 2024Deadline 31 Jan 2029
NIHUS FederalResearch GrantFY2025AddressAfrican AmericanAfrican American groupAfrican American individualAfrican American peopleAfrican American populationAfrican AmericansAfro AmericanAfroamericanAlcohol DrinkingAlcohol consumptionBaseline SurveysBiologic FactorBiological FactorsBloodBlood Reticuloendothelial SystemBreast CancerCancer BurdenCancer SurvivorCancer Susceptibility GeneCancer-Predisposing GeneCancersCessation of lifeCharacteristicsColorectal CancerConsentDNADNA SequenceDNA mutationDNA seqDNA sequencingDNAseqDataDeathDeath RateDeoxyribonucleic AcidDetectionDevelopmentDiagnosisDisparateEarly DiagnosisEndometrial CancerEndometrial CarcinomaEndometrium CancerEndometrium CarcinomaEnrollmentEnvironmental FactorEnvironmental Risk FactorEtOH drinkingEtOH useEthnic GroupEthnic PeopleEthnic PopulationEthnic individualEthnicity PeopleEthnicity PopulationFaceFemale Breast CancerFemale Breast CarcinomaFrequenciesFutureGene variantGeneral PopulationGeneral PublicGenesGeneticGenetic ChangeGenetic DiversityGenetic PredispositionGenetic Predisposition to DiseaseGenetic SusceptibilityGenetic VariationGenetic defectGenetic mutationGenetic propensityGenetic studyGenomeGenotypeGerm LinesHereditaryIncidenceInfrastructureInheritedInherited PredispositionInherited SusceptibilityInvestigationKnowledgeMalignant Breast NeoplasmMalignant NeoplasmsMalignant TumorMalignant Tumor of the LungMalignant neoplasm of lungMalignant neoplasm of prostateMalignant prostatic tumorMammary Carcinoma of the Female BreastMedicalMedical RecordsMorbidityMorbidity - disease rateMutationNational Cancer BurdenNon-HispanicNonhispanicNot Hispanic or LatinoObesityOutcomeParticipantPathogenicityPhenotypePopulationPopulation HeterogeneityPredisposition genePrevalencePreventionProstateProstate CAProstate CancerProstate GlandProstate malignancyProstatic GlandPulmonary CancerPulmonary malignant NeoplasmRaceRacesRacial GroupResearchResearch SpecimenRiskRisk FactorsRoleSNP arraySNP chipSalivaSecond CancerSecond Primary CancersSecondary MalignancySecondary Malignant NeoplasmSmokingSpecimenSurvey InstrumentSurveysSurvivorsSusceptibility GeneTestingTumor TissueUpdateVariantVariationWhole Bloodadiposityalcohol ingestionalcohol intakealcohol product usealcohol usealcoholic beverage consumptionalcoholic drink intakeallelic variantbreast cancer survivalcancer diagnosiscancer geneticscancer locationcancer predispositioncancer riskcancer sitecancer typeco-morbidco-morbiditycohortcomorbiditycorpulencedesigndesigningdevelopmentaldisparities in racedisparity due to racediverse populationsearly detectionenrollenvironmental riskethanol consumptionethanol drinkingethanol ingestionethanol intakeethanol product useethanol useethnic subgroupethnicity groupexome sequencingexome-seqexperiencefacesfacialgenetic etiologygenetic mechanism of diseasegenetic variantgenetic vulnerabilitygenetically predisposedgenome mutationgenome scalegenome-widegenomewidegenomic variantheterogeneous populationhigh risk grouphigh risk individualhigh risk peoplehigh risk populationimprovedinequality due to raceinequity due to racelow-frequency mutationlung cancermalignancymalignant breast tumormortalitymortality ratemortality ratiomulti-ethnicmultiethnicneoplasm/cancernon-geneticnongeneticnovelpolygenetic risk scorespolygenic risk scorepopulation diversitypredisposing generace based disparityrace based inequalityrace based inequityrace disparityrace related disparityrace related inequalityrace related inequityracialracial backgroundracial disparityracial diversityracial inequalityracial inequityracial originracial populationracial subgroupracially diverseracially unequalrare allelerare mutationrare variantresponserisk mitigationscreeningscreeningssecondary cancersingle nucleotide polymorphism arraysingle nucleotide polymorphism chipsocial rolesusceptibility allelesusceptibility locussusceptibility varianttumor
Description preview
Project Summary
Survival for breast, prostate and colorectal cancer has improved dramatically over the past three
decades as a result of advances in treatment and screening for the detection of these common
cancers at an earlier stage. However, African Americans (AAs) still suffer from a higher mortality
rate after diagnosis of these cancers…
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