grant
PROJECT 1
Organization NEW YORK UNIVERSITY SCHOOL OF MEDICINELocation NEW YORK, UNITED STATESPosted 1 Jul 2025Deadline 31 May 2030
NIHUS FederalResearch GrantFY2025AccelerationAddressAdverse ExperienceAdverse eventAllograftingAssayBackBioassayBioinformaticsBiological AssayBlood PlasmaBrain DeadBrain DeathBurkitt HerpesvirusBurkitt Lymphoma VirusCandidaCell BodyCellsClinicalClinical Decision Support SystemsCloud ComputingCloud InfrastructureComa DepasseCommunicable DiseasesDNA VirusesDataDetectionDevelopmentDiagnosisDomestic PigDorsumDrugsEB virusEBVEnsureEpstein Barr VirusExposure toFamily suidaeFunctional MetagenomicsFundingFutureGenomicsGoalsGrafting ProcedureHHV-4HHV4HSV-1HSV1HealthHeartHerpes Simplex Type 1Herpes Simplex Virus 1Herpes Simplex Virus Type 1Herpesvirus 1HeterograftHeterologous TransplantationHourHumanHuman Herpesvirus 4Immunochemical ImmunologicImmunologicImmunologicalImmunologicallyImmunologicsImmunosuppressionImmunosuppression EffectImmunosuppressive EffectIndustryInfectionInfectious DiseasesInfectious DisorderInfectious Mononucleosis VirusInformaticsKidneyKidney Urinary SystemLifeLinkMachine LearningMeasuresMedicationMetagenomicsMethodsMicrobeModalityModelingModern ManMoniliaNHP modelsNorovirusNorwalk-like VirusesNucleotidesOrganOrgan TransplantationOrgan TransplantsOrganismOutcomeOutputPatient CarePatient Care DeliveryPatientsPersonsPestivirus InfectionsPharmaceutical PreparationsPharmacogeneticsPhysiologyPigsPlasmaPlasma SerumProcessProtocolProtocols documentationRNA VirusesRegulatory approvalReportingReproducibilityResearch ResourcesResolutionResource InformaticsResourcesReticuloendothelial System, Serum, PlasmaSamplingScreening procedureSecureSiteSolidSpecificityStandardizationSuidaeSus scrofa domesticaSwineSystemTimeTransmissionTransplantationValidationViralVirusWaiting ListsXenograftXenograft procedureXenotransplantationZoonosesZoonoticZoonotic Infectionbio-informatics pipelinebiobankbioinformatics pipelinebiorepositorycardiac heterograftcardiac xenograftcare for patientscare of patientscaring for patientscerebral deathclinical decision supportcloud based computingcloud computerdesigndesigningdevelopmentaldrug/agentgenome editinggenomic editingheart heterograftheart xenografthepatic heterografthepatic xenograftherpes simplex iherpes simplex-1high riskimmune suppressionimmune suppressive activityimmune suppressive functionimmunosuppressedimmunosuppressive activityimmunosuppressive functionimmunosuppressive responseimprovedimproved outcomein vivo Modelinfection managementinfection riskkidney heterograftkidney xenograftliver heterograftliver xenograftliving systemmachine based learningmetagenome sequencingmetagenomic sequencingmicrobes genomemicrobialmicrobial genomemicrobial genomicsnano porenanoporenonhuman primate modelsnovelopen sourceorgan allograftorgan graftorgan xenograftpathogenpig genomeporcineportabilitypost-transplantpost-transplantationposttransplantposttransplantationpriority pathogenprospectiveregulatory authorizationregulatory certificationregulatory clearancerenalrenal heterograftrenal xenograftresolutionsscreeningscreening toolsscreeningssuccesssuidsupport toolstransmission processtransplanturinaryuser-friendlyvalidationswaitlistweb interfacexeno-transplantxeno-transplantation
Description preview
Project Abstract: U19 Project 1
Dynamic Surveillance and Clinical Support for Control of Xenotransplant-Related Pathogens
The future success of pig-to-human xenotransplantation is dependent on the provision of pathogen-free organs
and robust microbial surveillance post-transplant when human recipients are heavily immunosuppressed.
Decades of…
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