grant

Probing the flexibility of G0

Organization UNIVERSITY OF MICHIGAN AT ANN ARBORLocation ANN ARBOR, UNITED STATESPosted 1 Aug 2023Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AgingBiologicalBody TissuesCancersCell BodyCell Communication and SignalingCell CycleCell Cycle ControlCell Cycle InhibitionCell Cycle RegulationCell Division CycleCell SignalingCellsDevelopmentEventFertilized EggFertilized OvumG0 PhaseG0 stateGoalsIntracellular Communication and SignalingMalignant NeoplasmsMalignant TumorMetabolicMolecularNutrient availabilityOrganOrganismPathway interactionsPhysiologicPhysiologicalProcessProductionSeriesSignal TransductionSignal Transduction SystemsSignalingTissuesWorkadult animalbiologicbiological signal transductiondaughter celldevelopmentalflexibilityflexibleliving systemmalignancymature animalneoplasm/cancerpathwayregenerate new tissueregenerate tissueregenerating damaged tissueregenerating tissueresponsetissue regenerationtissue regrowthtissue renewaltissue specific regenerationtoolzygote
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Project Summary/Abstract
The cell cycle is an ordered series of molecular events in a cell leading to division and production of two

daughter cells. This process is fundamental to the development of all multicellular organisms, which begin from

a single cell, the fertilized egg. Equally important for proper development though, is the slowing or…

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