grant
Predicting Post-Covid Pulmonary Fibrosis with Explainable Deep Learning and Optimal Biomarker Discovery
Organization NORTHWESTERN UNIVERSITYLocation CHICAGO, UNITED STATESPosted 1 Sept 2024Deadline 31 May 2028
NIHUS FederalResearch GrantFY2025Active Follow-upAcuteAddressAdipose tissueAdrenal Cortex HormonesAffectAirway challengeAlgorithmsAreaBiological MarkersBody CompositionBone structureBreathlessnessCAT scanCOVID crisisCOVID epidemicCOVID pandemicCOVID survivorsCOVID-19COVID-19 crisisCOVID-19 epidemicCOVID-19 eraCOVID-19 global health crisisCOVID-19 global pandemicCOVID-19 health crisisCOVID-19 infectionCOVID-19 infection survivorsCOVID-19 pandemicCOVID-19 periodCOVID-19 public health crisisCOVID-19 survivorsCOVID-19 virus infectionCOVID-19 yearsCOVID19 infectionCT X RayCT XrayCT imagingCT scanCV-19CapsulesCessation of lifeCharacteristicsClinicalClinical EvaluationClinical TestingComputed TomographyConfidence IntervalsCoronavirus Infectious Disease 2019CorticoidsCorticosteroidsDataData SetDeathDetectionDevelopmentDiagnosisDiagnosticDiseaseDisorderDrugsDyspneaEarly DiagnosisEarly InterventionEarly identificationElectronic Health RecordEmergenciesEmergency SituationEvaluationExhibitsFactor AnalysesFactor AnalysisFatty TissueFibrosisFibrotic lesions in lungFutureGoalsHealth CareHealth Care SystemsHumanImageIndividualLaboratoriesLong COVIDLong COVID-19Long coronavirus diseaseLong coronavirus disease 2019Long-Term EffectsLungLung GraftingLung Respiratory SystemLung Tissue FibrosisLung TransplantationLung damageLung scarLung symptomLung tissue scarMeasurementMechanical Ventilator WeaningMedicationMethodsModalityModelingModern ManMorbidityMorbidity - disease rateMuscleMuscle TissueMusculoskeletal SystemNational Institutes of HealthNeurocognitiveOutcomePatientsPatternPennsylvaniaPersonal SatisfactionPersonsPharmaceutical PreparationsPhasePopulationPredicting RiskPropertyPublic HealthPulmonary FibrosisPulmonary GraftPulmonary ScarPulmonary Tissue fibrosisPulmonary TransplantPulmonary TransplantationRadiographyReportingRespirator WeaningRiskRoentgenographySARS-CoV-2 epidemicSARS-CoV-2 global health crisisSARS-CoV-2 global pandemicSARS-CoV-2 infectionSARS-CoV-2 pandemicSARS-CoV-2 survivorsSARS-CoV2 infectionSARS-coronavirus-2 epidemicSARS-coronavirus-2 pandemicScanningScarring at the lungScarring in the lungSevere Acute Respiratory Syndrome CoV 2 epidemicSevere Acute Respiratory Syndrome CoV 2 pandemicSevere acute respiratory syndrome coronavirus 2 epidemicSevere acute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 pandemicSeverity of illnessSkeletal MuscleSymptomsTestingTextureTherapeuticThickThicknessTomodensitometryTrainingTranslationsUnited States National Institutes of HealthUniversitiesVaccinationVariantVariationVentilator WeaningVisceralVisualVoluntary MuscleWorkX-Ray CAT ScanX-Ray Computed TomographyX-Ray Computerized TomographyXray CAT scanXray Computed TomographyXray computerized tomographyactive followupadiposebio-markersbiologic markerbiomarkerbiomarker discoverybiomarker selectioncapsulecare seekingcatscanchest CTchest computed tomographychronic COVIDchronic COVID-19chronic novel coronavirus disease 2019chronic symptomclinical centerclinical practiceclinical testco-morbidco-morbiditycombatcomorbiditycomputed axial tomographycomputer tomographycomputerized axial tomographycomputerized tomographycoronavirus disease 2019coronavirus disease 2019 crisiscoronavirus disease 2019 epidemiccoronavirus disease 2019 global health crisiscoronavirus disease 2019 global pandemiccoronavirus disease 2019 health crisiscoronavirus disease 2019 infectioncoronavirus disease 2019 pandemiccoronavirus disease 2019 public health crisiscoronavirus disease crisiscoronavirus disease epidemiccoronavirus disease pandemiccoronavirus disease-19coronavirus disease-19 global pandemiccoronavirus disease-19 pandemiccoronavirus infectious disease-19deep learningdeep learning algorithmdeep learning methoddeep learning strategydevelopmentaldisease severitydrug/agentearly detectionelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordexhaustexperiencefibrosis in the lungfibrotic lungfollow upfollow-upfollowed upfollowupforecasting riskimagingimprovedindividual patientinfected with COVID-19infected with COVID19infected with SARS-CoV-2infected with SARS-CoV2infected with coronavirus disease 2019infected with severe acute respiratory syndrome coronavirus 2innovateinnovationinnovativeknowledge databaselife-threatening COVIDlife-threatening COVID-19life-threatening SARS-CoV-2life-threatening coronavirus diseaselife-threatening coronavirus disease 2019life-threatening severe acute respiratory syndrome coronavirus 2locomotor systemlong haul COVIDlong haul COVID-19long haul coronavirus diseaselong haul coronavirus disease 2019long-hauler COVIDlong-hauler COVID-19long-hauler coronavirus disease 2019long-hauler syndromelong-term COVIDlong-term COVID-19long-term coronavirus diseaselong-term coronavirus disease 2019lung fibrosislung functionlung injurylung lobelung rehabilitationlung transplantmortalitymulti-modal datamulti-modal datasetsmulti-modalitymultimodal datamultimodal datasetsmultimodalitymuscularnon-contrast CTnoncontrast CTnoncontrast computed tomographynovelpersistent COVID-19persistent symptompost COVID syndromepost COVID-19 syndromepost acute COVID syndromepost acute COVID-19post acute COVID-19 syndromepost acute SARS-CoV-2post acute coronavirus disease 2019post acute coronavirus disease 2019 syndromepost acute coronavirus disease syndromepost acute severe acute respiratory syndrome coronavirus 2post coronavirus disease 2019 syndromepost coronavirus disease syndromepost-COVIDpost-COVID pulmonary fibrosispost-COVID-19post-COVID-19 pulmonary fibrosispost-acute phases of COVID-19post-coronavirus disease 2019potential biological markerpotential biomarkerpredict riskpredict riskspredicted riskpredicted riskspredicting riskspredictive riskpredicts riskprolonged COVID-19 symptomspulmonarypulmonary damagepulmonary functionpulmonary injurypulmonary rehabilitationpulmonary symptompulmonary tissue damagepulmonary tissue injuryradiological imagingresearch clinical testingrespiratory challengerisk predictionrisk predictionsserious COVIDserious COVID-19serious SARS-CoV-2serious coronavirus diseaseserious coronavirus disease 2019serious severe acute respiratory syndrome coronavirus 2severe COVIDsevere COVID-19severe COVID19severe SARS-CoV-2severe acute respiratory syndrome coronavirus 2 global health crisissevere acute respiratory syndrome coronavirus 2 global pandemicsevere coronavirus diseasesevere coronavirus disease 19severe coronavirus disease 2019severe severe acute respiratory syndrome coronavirus 2skeletal structurestandard of carestatisticssubcutaneoussubdermalsuccesssurvive COVID-19survive SARS-CoV-2tooltranslationtreatment strategywell-beingwellbeingwhite adipose tissueyellow adipose tissue
Description preview
PROJECT SUMMARY
Since the beginning of COVID-19 (SARS-CoV-2) pandemic, we have seen a number of prominent variants, and
two of them are very recent. COVID-19 continues to affect millions of people: over 771 million people were
affected and over 6.9 million deaths occurred (as of October 2023). A significant portion of patients who suffer
from…
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