grant
Population genetic modeling of genetic variation for complex traits and diseases
Organization UNIVERSITY OF CHICAGOLocation CHICAGO, UNITED STATESPosted 1 Sept 2023Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AccountingBiologyComplexDNA mutationDataData SetDevelopmentDiagnosisDiseaseDisorderEventEvolutionExhibitsGeneticGenetic ChangeGenetic DiversityGenetic ModelsGenetic VariationGenetic defectGenetic mutationGenomic SegmentHeritabilityHumanHuman GeneticsLearningMath ModelsMeasurementMethodsModelingModern ManModernizationMutationPatternPhenotypePopulationPopulation GeneticsProcessResearchResearch ResourcesResourcesRiskRoleShapesSiteStatistical MethodsStratificationVariantVariationWorkbiobankbiorepositorydevelopmentaldisease riskdisorder riskexomegenetic architecturegenetic associationgenome mutationgenome scalegenome segmentgenome sequencinggenome-widegenomewidegenomic regionimprovedmathematic modelmathematical modelmathematical modelingnon-geneticnongeneticpolygenic predictorspolygenic scorespressuresocial rolestatistic methodstooltrait
Description preview
Project Summary
Many phenotypes, as well as the risk of developing many diseases, are genetically complex, and
involve contributions from both genetic and non-genetic factors. Work in human genetics over the
past two decades have shown that this variation is the result of contributions from a very large
number of sites, on the order of thousands…
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