grant
Polyclonal Bi-Specific Vectored ImmunoTherapy to Functionally Cure HIV Infection
Organization MASSACHUSETTS GENERAL HOSPITALLocation BOSTON, UNITED STATESPosted 15 May 2024Deadline 31 Mar 2029
NIHUS FederalResearch GrantFY2026AIDS VirusAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAnimal ModelAnimal Models and Related StudiesAnti-Retroviral AgentsAntibodiesAssayBioassayBiological AssayCell BodyCellsCommunicable DiseasesDevelopmentDoctor of PhilosophyDoseDrugsEngineeringEscape MutantGene TransferGrantHIVHIV InfectionsHIV cureHIV functional cureHIV individualsHIV infected individualsHIV infected personsHIV interventionHIV peopleHIV positive individualsHIV positive peopleHIV replicationHIV therapeuticHIV therapyHIV treatmentHIV viral infectionHIV viral replicationHIV virus infectionHIV-1HIV-1 cureHIV-1 functional cureHIV-1 infectionHIV-1 interventionHIV-1 replicationHIV-1 therapeuticHIV-1 therapyHIV-1 treatmentHIV-1 viral replicationHIV-1 virus replicationHIV-IHIV/AIDS cureHIV1HealthHuman Immunodeficiency Virus Type 1Human Immunodeficiency Virus therapyHuman Immunodeficiency Virus treatmentHuman Immunodeficiency Virus-1Human Immunodeficiency VirusesHuman immunodeficiency virus 1Immune mediated therapyImmune responseImmune systemImmunologically Directed TherapyImmunotherapyIndividualInfectionInfection by HIV-1Infection from HIV-1Infection of HIV-1Infectious DiseasesInfectious DisorderLAV-HTLV-IIILaboratoriesLymphadenopathy-Associated VirusMedicationMiceMice MammalsMissionMurineMusNHP modelsNIDANational Institute of Drug AbuseNational Institute on Drug AbuseNational Institutes of HealthOutcomePLWHPWHPersonsPh.D.PhDPharmaceutical PreparationsPrincipal InvestigatorRegimenResearchSeriesSubstance Use DisorderTechnologyTestingTherapeutic InterventionUnited States National Institutes of HealthVirusVirus-HIVanti-retroviraldesigndesigningdevelopmentaldrug/agentengineered immune systemexperimentexperimental researchexperimental studyexperimentshost responsehuman immunodeficiency virus curehuman immunodeficiency virus infectionhuman immunodeficiency virus replicationhuman immunodeficiency virus-1 replicationimmune engineeringimmune system responseimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapiesimmune-based treatmentsimmuno therapyimmunoengineeringimmunoresponseimprovedin vivoindividuals infected with HIVindividuals with HIVindividuals with human immunodeficiency virusinfected with HIVinfected with human immunodeficiency virusintervention therapymedical collegemedical schoolsmodel of animalnew drug classnonhuman primate modelsnovelnovel drug classpeople infected with HIVpeople infected with human immunodeficiency viruspeople living with HIVpeople with HIVpeople with human immunodeficiency viruspolyclonal antibodyprofessorschool of medicinesubstance use and disordertreat HIVtreat Human Immunodeficiency Virusvector
Description preview
Project Summary / Abstract
This proposal describes the framework of a DP1 grant for Alejandro B. Balazs, PhD.
Dr. Balazs is currently an assistant professor at Harvard Medical School and a principal
investigator at the Ragon Institute of MGH, MIT & Harvard. Dr. Balazs' research is focused on
engineering the immune system via gene transfer as a…
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