grant
Plasticity of the Retinogeniculate Synapse
Organization BOSTON CHILDREN'S HOSPITALLocation BOSTON, UNITED STATESPosted 1 Sept 2003Deadline 31 May 2030
NIHUS FederalResearch GrantFY20252-photon21+ years old3-D3-Dimensional3DAdultAdult HumanAgeAmblyopiaApoplexyAstrocytesAstrocytusAstrogliaAttentionBrainBrain Nervous SystemBrain Vascular AccidentCell NucleusCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeChronicComplexConfocal MicroscopyCranial Nerve II InjuriesDataDendritesDevelopmentDiseaseDisorderDorsalElectrophysiologyElectrophysiology (science)EncephalonExperimental ModelsExposure toFGF ReceptorsFGF-RFGFRFibroblast Growth Factor Receptor FamilyFibroblast Growth Factor ReceptorsFundingFutureGeneticGliaGlial CellsHeadImageImmunohistochemistryImmunohistochemistry Cell/TissueImmunohistochemistry Staining MethodIn VitroIndividualInjuryKolliker's reticulumLabelLateral Geniculate BodyMiceMice MammalsModelingMurineMusNatureNerve CellsNerve UnitNeural CellNeurocyteNeurogliaNeuroglial CellsNeuronsNeurophysiology / ElectrophysiologyNon-neuronal cellNonneuronal cellNucleusOptic Nerve InjuriesOptic Nerve TraumaPhasePlayPopulationProcessRecoveryRetinaRetinal DegenerationRetinal Ganglion CellsRoleSecond Cranial Nerve InjuriesSecond Cranial Nerve TraumaSightSliceStrokeStructureSynapsesSynapticSynaptic plasticityTestingThalamic structureThalamusTimeTransmission Electron MicroscopyTraumatic Optic NeuropathyVisionVision DisordersVisualVisual DisorderVisual PathwaysVisual PerceptionVisual SystemVisualizationWeightWorkadulthoodagesastrocytic gliaawakebrain attackcell typecerebral vascular accidentcerebrovascular accidentdegenerative retina diseasesdeprivationdesigndesigningdevelopmentaldevelopmental plasticityelectrophysiologicalexperienceexperimentexperimental researchexperimental studyexperimentsimagingin vivoin vivo two-photon imaginginjuriesinsightlateral geniculatelateral geniculate nucleuslenslensesmouse geneticsnerve cementneuronalnew approachesnovel approachesnovel strategiesnovel strategypermissivenesspostnatalpreferencereconstructionrepairrepairedresponseretina degenerationretinal degenerativeretinal degenerative diseasesretinal ganglionretinogeniculatesocial rolespatial relationshipstrokedstrokessynapsethalamicthree dimensionaltooltwo-photonvisual deprivationvisual functionvisual informationvisual stimulusweights
Description preview
ABSTRACT
There is growing evidence that subcortical regions of the early visual pathway are not simple relays of primary
visual information but play a greater role in visual system processing and plasticity than previously
acknowledged. One such example is the primary visual thalamus, the dorsal lateral geniculate nucleus (dLGN).
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