grant
Photoreceptor induction in wounded corneas
Organization UNIVERSITY OF WASHINGTONLocation SEATTLE, UNITED STATESPosted 1 Sept 2024Deadline 31 May 2029
NIHUS FederalResearch GrantFY2025AccelerationAcuteAffectAgonistBlindnessBody TissuesCRE RecombinaseCell BodyCell Communication and SignalingCell Culture TechniquesCell Growth in NumberCell LineCell MultiplicationCell ProliferationCell SignalingCellLineCellsCellular ProliferationCicatrixCollaborationsCommunicationCorneaCorneal InjuryDREADDsDarknessEnterobacteria phage P1 Cre recombinaseEnvironmentEpithelial CellsExposure toEyeEyeballFutureGene ExpressionGenesGeneticGoalsHealthHistoryHumanIlluminationImmediate-Early GenesImpairmentIn VitroInjuryIntracellular Communication and SignalingIntracellular Second MessengerKO miceKnock-out MiceKnockout MiceLaboratoriesLightLightingLoxP-flanked alleleMacacaMacaqueMeasuresMediatingMiceMice MammalsModern ManMolecularMonitorMotilityMurineMusNatureNull MouseOpsinOpticsPansyParacrine CommunicationParacrine SignalingPhosphorylationPhotoradiationPhotoreceptor CellPhotoreceptorsPhotosensitive CellPhotosensitiveness due to sunPhotosensitivityPhysiologicPhysiologicalPlayPrimatesPrimates MammalsProtein PhosphorylationProteinsRecording of previous eventsRegimenRegulationReporterRestRetinaRod-OpsinRoleScarsSecond Messenger SystemsSecond MessengersSightSignal TransductionSignal Transduction SystemsSignalingStrains Cell LinesSurfaceSystemTechniquesTestingTherapeuticTissuesUpregulationViolaVioletVisionVisualVisual ReceptorVisual SystemVisualizationWorkWound Repairantagonismantagonistbacteriophage P1 recombinase Crebiological signal transductioncell culturecell culturescircadian clockcircadian pacemakercornealcorneal epithelialcorneal epithelial wound healingcorneal epitheliumcorneal healingcorneal regenerationcorneal woundcorneal wound healingcultured cell linedesigner receptors exclusively activated by designer drugsexperimentexperimental researchexperimental studyexperimentsexposure to lightexposure to visible lightfloxedfloxed allelehealinghistoriesin vivoinjuriesinnovateinnovationinnovativelight exposurelight pollution exposuremigrationmouse modelmurine modelnon-human primatenonhuman primatenovelopticalparacrinere-epithelializationresponsesignal transduction second messengerssocial rolesun sensitivitytherapeutic targettissue woundtranslational opportunitiestranslational potentialvision lossvisual functionvisual losswoundwound closurewound healingwound recoverywound resolutionwoundingwounds
Description preview
Project Summary/Abstract
The cornea is the optically clear, curved tissue that provides the majority of refractive power in
the eye. Improper healing of corneal wounds is a serious issue that can lead to blindness or
permanent refractive visual complications. We have demonstrated that the cornea becomes
intrinsically photoreceptive after injury,…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click