grant
Personalized Therapies of Pediatric Sepsis
Organization UNIVERSITY OF PITTSBURGH AT PITTSBURGHLocation PITTSBURGH, UNITED STATESPosted 1 Feb 2025Deadline 31 Jan 2030
NIHUS FederalResearch GrantFY20250-11 years old21+ years oldAdmissionAdmission activityAdultAdult HumanAffectAlgorithmsCathetersCharacteristicsChildChild YouthChildhoodChildren (0-21)ClinicalClinical MarkersClinical TrialsCluster AnalysesCluster AnalysisCommunicable DiseasesComplementComplement ProteinsComputational TechniqueCritical CareCritically ill childrenDataData BasesData SetDatabasesDetectionDevelopmentDevelopment PlansDiagnosisDiagnosticDiseaseDisease OutcomeDisease ProgressionDisorderDysfunctionEarly DiagnosisEarly identificationEarly treatmentElectronic Health RecordEvaluationEvaluation StudiesEvolutionFailureFeverFoundationsFrequenciesFunctional disorderFutureGoalsHealth Care CostsHealth CostsHealth ExpendituresHeterogeneityHospitalsInfectionInfectious DiseasesInfectious DisorderInformaticsInstitutionInvestigatorsKnowledgeLength of StayLifeMachine LearningMeasurementMeasuresMentorshipModelingNumber of Days in HospitalOrganOrgan failurePatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPatternPediatric cohortPediatricsPersonsPhenotypePhysiciansPhysiologicPhysiologicalPhysiologyPhysiopathologyPopulationPositionPositioning AttributePredictive AnalyticsPredictive ValuePreventionPyrexiaResearchResearch PersonnelResearchersSepsisSeptic ShockSiteSubgroupSyndromeTestingTherapeuticTimeTrainingValidationVenousWorkadulthoodanalytical toolantisepsis treatmentblood infectionbloodstream infectioncareer developmentchild patientschildren with sepsisclinical biomarkersclinical phenotypeclinical promptclinically useful biomarkerscomplementationcostcritically ill childdata basedesigndesigningdevelopmentaldigital promptearly detectionearly therapyelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordfebrilefebrishealth care expenditureheart rate variabilityhospital dayshospital length of stayhospital stayimprovedimproved outcomeindividualized therapeuticinfection in the bloodinfection of the bloodinsightkidsmachine based learningmedical expendituremortalitymultidisciplinaryneonatal patientneonatal sepsisoutcome predictionpathogenpathophysiologypatient centeredpatient orientedpatient oriented outcomespediatricpediatric patientspediatric sepsispediatric septicpersonalization of treatmentpersonalized medicinepersonalized therapeuticpersonalized therapypersonalized treatmentprediction algorithmpredictive toolspreventpreventingprognostic abilityprognostic powerprognostic utilityprognostic valueresponsesepsis caresepsis in childrensepsis interventionssepsis managementsepsis therapeuticssepsis therapysepsis treatmentseptic childrenseptic therapyseptic treatmentsevere sepsisseverely septicskillstreat sepsisvalidationsyoungster
Description preview
PROJECT ABSTRACT
Sepsis is a life-threatening condition characterized by a dysregulated response to infection, leading to
significant organ dysfunction and affecting 75,000 children and one million adults each year. The estimated
yearly impact of this disease is 200,000 lives lost and $20 billion dollars in healthcare expenditures.
Unfortunately,…
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