grant
Peripheral nervous system aging
Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 30 Sept 2025Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY2025AddressAfricanAgeAgingBiologic ModelsBiologic PhenomenaBiological ModelsBiological PhenomenaBiology of AgingBloodBlood Reticuloendothelial SystemBrainBrain Nervous SystemCell BodyCellsCommunicationComplexCoupledDeteriorationDiseaseDisorderEncephalonImmuneImmunesIncrease lifespanKillifishesLength of LifeLongevityMachine LearningMethodsMiceMice MammalsModel SystemMurineMusNerve CellsNerve UnitNeural CellNeurocyteNeuronsOrganPeripheralPeripheral Nervous SystemProcessRoleStimulusSystemTimeWorkage associated alterationsage associated changesage correlated alterationsage correlated changesage dependent alterationsage dependent changesage induced alterationsage induced changesage related alterationsage related changesage reversalage specific alterationsage specific changesaged brainagesaging associated alterationsaging associated changesaging brainaging correlated alterationsaging correlated changesaging dependent alterationsaging dependent changesaging induced alterationsaging induced changesaging processaging related alterationsaging related changesaging reversalaging specific alterationsaging specific changesalleviate age relatedalleviate agingalterations with ageameliorating agingboost longevitycell typechanges with agecounter age relatedcounter agingcounteract age relatedcounteract agingelongating the lifespanenhance longevityextend life spanextend lifespanextend longevityfoster longevityhigh rewardhigh riskimprove lifespanimprove longevityin vivoinnervationinterestlifespan extensionmachine based learningnerve supplyneuronalprolong lifespanprolong longevitypromote lifespanpromote longevityreverse agereverse agingreverse aging effectsreversible agingsocial rolespatial RNA sequencingspatial gene expression analysisspatial gene expression profilingspatial resolved transcriptome sequencingspatial transcriptome analysisspatial transcriptome profilingspatial transcriptome sequencingspatial transcriptomicsspatially resolved transcriptomicsspatio transcriptomicssupport longevitytool
Description preview
Summary
Aging alters the function of every organ. An inherent limitation to our understanding of aging is
the complexity of the aging process. Thus, fundamental questions remain entirely unanswered:
Are there mechanisms that coordinate organ function and how do they deteriorate with age?
Could such mechanisms be restored to promote longevity?…
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