grant

Optimizing Pharmacotherapy with Noninvasive Wearable Sensors and Subscalp EEG

Organization MAYO CLINIC ROCHESTERLocation ROCHESTER, UNITED STATESPosted 4 Feb 2022Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY2025AffectAutomobile DrivingBehavioralBenzodiazepine CompoundsBenzodiazepinesBiological MarkersBleedingCardiac ChronotropismCell Communication and SignalingCell SignalingChronicClinicalConvNetConvulsive SeizuresDataDetectionDevicesDiseaseDisorderDoseDrug TherapyDrugsEEGElectrodesElectroencephalogramElectroencephalographyElectrophysiologyElectrophysiology (science)EnvironmentEpilepsyEpileptic SeizuresEpilepticsEventFDA approvedFeasibility StudiesGoalsHeart RateHemorrhageHospitalsImplantIncidenceInternationalIntracellular Communication and SignalingMedicalMedicationMethodsMonitorMotor SeizuresNatureNeurophysiology / ElectrophysiologyPatient MonitoringPatient RecruitmentsPatientsPatternPharmaceutical PreparationsPharmacological TreatmentPharmacotherapyPhysiciansPhysiologicPhysiologicalProbabilityProcessPublishingQOLQuality of lifeReportingResearchRiskScalpScalp structureSeizure DisorderSeizuresSelf AdministeredSelf AdministrationSignal TransductionSignal Transduction SystemsSignalingSurrogate MarkersSystemTelemetriesTelemetryTestingTimeVendorWorkWristalgorithm developmentalgorithm trainingbio-markersbiologic markerbiological signal transductionbiomarkerblood lossbody sensorbody worn sensorcohortconvolutional networkconvolutional neural netsconvolutional neural networkdata acquisitiondata acquisitionsdata captured from wearablesdata collected from wearablesdata collected using wearablesdata gathered from wearabledata gathered through wearablesdata gathered via wearabledata streamsdata to traindataset to traindrivingdrug interventiondrug treatmentdrug/agentelectrophysiologicalempowermentepilepsiaepilepsy monitoringepilepsy participantepilepsy patientepilepsy recordingepilepsy subjectepilepsy trackingepilepsy volunteerepileptic monitoringepileptic patientepileptic recordingepileptic subjectepileptiform monitoringepileptiform recordingepileptiform trackingepileptogenicepileptogenic monitoringexperiencefeasibility trialhandheld devicehandheld equipmentinfection riskinnovateinnovationinnovativemachine learning based methodmachine learning methodmachine learning methodologiesnovelparticipant recruitmentpatients with epilepsypharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticspreventpreventingprospectivesafety and feasibilitysafety assessmentseizure detectionseizure monitoringseizure recordingseizure trackingsensorside effectsurrogate bio-markerssurrogate biomarkerstargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttelemetrictraining datausabilitywearablewearable biosensorwearable datawearable devicewearable device datawearable electronicswearable sensorwearable sensor datawearable sensor technologywearable systemwearable technologywearable toolwearables
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Description preview

Project Summary
The apparently random nature of seizures is one of the most significant factors affecting quality of life for patients

with epilepsy. Accurate seizure forecasting could be transformative for patients with epilepsy, allowing patients

to modify activities to avoid risk, take fast-acting medications to stop seizures before they…

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