grant
Nutrition Intervention Trials
Organization DIVISION OF CANCER EPIDEMIOLOGY AND GENETICSLocation UNITED STATES
NIHUS FederalResearch GrantFY2025Active Follow-upAgeBiologicalBloodBlood Reticuloendothelial SystemBlood SerumBody TissuesBronchiBurkitt HerpesvirusBurkitt Lymphoma VirusC pyloriC. pyloriCampylobacter pyloriCancer Death RatesCancer InductionCancersCardiaCarotenes and CarotenoidsCarotenoidsCategoriesCausalityChinaCohort StudiesConcurrent StudiesConsumptionCristobaliteCytologyData AnalysesData AnalysisDeath RateDietary InterventionDiseaseDisorderDouble-Blind MethodDouble-Blind StudyDouble-BlindedDouble-Masked MethodDouble-Masked StudyDysplasiaEB virusEBVEpstein Barr VirusEsophageal CancerEsophagusEsophagus CancerEtiologyFoodFumonisinsGastric Body CancerGastric CancerGastric Cardia CancerGastric Fundus CancerGastric Pylorus CancerGeneral PopulationGeneral PublicGenetic PolymorphismGenetic RiskGoiterH pyloriH pyloryH. pyloriH. pyloryHHV-4HHV4HPVHPV 16HPV-16HPV16Helicobacter pyloriHuman Herpesvirus 4Human Papilloma VirusHuman PapillomavirusHuman papilloma virus type 16Human papillomavirus 16Human papillomavirus type 16IncidenceInfectious Human Wart VirusInfectious Mononucleosis VirusIngestionInterventionIntervention StudiesIntervention TrialInterventional trialLungLung Respiratory SystemMainland ChinaMalignant Esophageal NeoplasmMalignant Esophageal TumorMalignant Gastric NeoplasmMalignant Gastric TumorMalignant NeoplasmsMalignant TumorMalignant Tumor of the EsophagusMalignant Tumor of the LungMalignant neoplasm of esophagusMalignant neoplasm of lungMicronutrientsMilletMineralsNitrosaminesNutrientNutrition InterventionsNutritional InterventionsPLRAParticipantPatient Self-ReportPersonsPlacebo ControlPleuraPleural TissuePreventionProbabilityProliferatingPulmonary CancerPulmonary malignant NeoplasmRandomizedResearch SpecimenRiskSandSe elementSeleniumSelf-ReportSerologySerumSilicaSilicon DioxideSolateneSpecimenStomachStomach CancerStructure of nail of toeSupplementationTestingTissuesToe NailToenailTooth LossTracheaTrachea ProperTraumaTridymiteVegetablesVitamin EVitaminsZincZn elementactive followupagesbeta,beta-Carotenebiologiccancer riskcarcinogenesiscarotenoid biosynthesiscausationdata interpretationdiet interventiondietary vegetabledisease causationdyscrasiaesophageal cancer preventionfollow upfollow-upfollowed upfollowupgastricgastric cardiagastric malignancyhistological sampleshistological specimenshistology sampleshistology specimenshuman papilloma virus 16ingestintervention researchinterventional researchinterventional studyinterventions researchlung cancermalignancymalignant stomach neoplasmmalignant stomach tumormortalitymortality ratemortality rationeoplasm/canceroesophageal cancerplacebo controlledpolymorphismpost interventionrandomisationrandomizationrandomly assignedstomach cardiastomach fundus cancerstomach pylorus cancertype 16 Human papilloma virustype 16 Human papillomaviruswart viruswindpipeα-Tocopherolβ-Carotene
Description preview
OBJECTIVE: The primary objective of this project is to determine if supplementation with multiple vitamin-minerals reduces the incidence and mortality of esophageal cancer, gastric cancer, and total mortality. Secondary objectives are to assess supplement effects on intermediate endpoints in carcinogenesis and to examine new hypotheses relating to…
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