grant

Novel Substituted Steroid Hormones

Organization EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENTLocation UNITED STATES
NIHUS FederalResearch GrantFY2025AerosolsAndrogenic AgentsAndrogenic CompoundsAndrogensBioavailabilityBiological AvailabilityBlood SerumDoseDrug PrecursorsDrugsEmployeeEndocrine TherapyFormulationGelGoalsHormonalHormonal TherapyHourImplantInjectionsLegal patentMale ContraceptionMale Contraceptive AgentsMale ContraceptivesMedicationMethodsModificationNICHDNational Institute of Child Health and Human DevelopmentNeedlesOralPatentsPharmaceutical PreparationsPhysiologic AvailabilityPro-DrugsProcessProdrugsProductionPropertyPublicationsR-Series Research ProjectsR01 MechanismR01 ProgramReportingResearch GrantsResearch Project GrantsResearch ProjectsScientific PublicationSerumSpermSpermatogenesisSpermatozoaSteroid CompoundSteroidsTesticlesTestisTestosteroneTherapeutic AndrogenTherapeutic Steroid HormoneTherapeutic TestosteroneTrans-TestosteroneTransactivationandrogen dependentandrogen responsiveandrogen sensitiveandrogenicdrug candidatedrug/agenthormone therapyhypothalamic pituitary axisinterestinventionlead candidatemale antifertility drugnew chemical entitynovelreceptor bindingreceptor boundsperm cellsteroid hormonetrans-activationzoosperm
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Description preview

The research project has a goal to develop novel male contraceptive agents. Candidate drugs have been developed and have been submitted for patents through employee invention reports. After review of these reports, it was determined that a provisional patent applications would be submitted by NICHD. This class of steroid core molecules could be a…

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