grant
Nitrile Imine Assisted Ligation Approaches to ADC synthesis
Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
Description preview
Antibody Drug Conjugates (ADCs) are an emerging class of chemologics which have wide ranging applications from target validation to new therapeutics. Currently, only a limited palette of synthetic approaches have been employed to attach the drug payload to the parent mAb. The proposed study aims to exploit novel reactivity and selectivity patterns…
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