grant
Neuronal and Vascular Interactions in the Visual System
Organization HARVARD MEDICAL SCHOOLLocation BOSTON, UNITED STATESPosted 1 Apr 2026Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY20262-photon3-D3-Dimensional3DAD dementiaAccelerationAcetylcholineAddressAdventitial CellAffectAge related macular degenerationAge-Related MaculopathyAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimers DementiaApplications GrantsArteriesBMXBMX Non-Receptor Tyrosine Kinase GeneBMX geneBehavioralBiologyBlindnessBlood PressureBlood Vessel ImagingBlood VesselsBlood capillariesBlood flowBody TissuesBrainBrain Nervous SystemCNS Nervous SystemCalciumCapillary Endothelial CellCell BodyCell Communication and SignalingCell SignalingCellsCentral Nervous SystemCerebrovascular systemCessation of lifeChelating AgentsChelatorsChloride ChannelsChloride Ion ChannelsClinicalComplexonsDataData BasesDatabasesDeathDegenerative Neurologic DisordersDevelopment PlansDiabetic RetinopathyDiagnosisDiseaseDisorderDoctor of PhilosophyDysfunctionETK GeneElectrophysiologyElectrophysiology (science)EncephalonEndothelial CellsEndotheliumEnsureEnvironmentEventEye diseasesFoundationsFunctional disorderFutureGeneticGlaucomaGoalsGrant ProposalsHumanImageImpairmentIn SituIntracellular Communication and SignalingInvestigatorsIon ChannelIonic ChannelsK channelKnowledgeKnowledge acquisitionLeadershipLightLight SensitivityLinkMembrane ChannelsMentorsMetabotropic Glutamate ReceptorsMiceMice MammalsModelingModern ManMolecularMurineMusNerve CellsNerve DegenerationNerve Transmitter SubstancesNerve UnitNervous System Degenerative DiseasesNeural CellNeural Degenerative DiseasesNeural degenerative DisordersNeuraxisNeurobiologyNeurocyteNeurodegenerative DiseasesNeurodegenerative DisordersNeurologic Degenerative ConditionsNeuron DegenerationNeuronal DysfunctionNeuronsNeurophysiology - biologic functionNeurophysiology / ElectrophysiologyNeurosciencesNeurotransmittersNeurovascular dysfunctionOutcomes ResearchPSCTK2 GenePSCTK3 GenePaperPathway interactionsPericapillary CellPericytesPerivascular CellPh.D.PhDPhotic StimulationPhotophobiaPhotoradiationPhysiologicPhysiologicalPhysiopathologyPlayPostdocPostdoctoral FellowPotassium ChannelPotassium Ion ChannelsPreparationPreventionPrimary Senile Degenerative DementiaPrimary visual cortexProcessReceptor ProteinResearchResearch AssociateResearch PersonnelResearchersResource DevelopmentRetinaRetinal Blood VesselsRetinal Vein OcclusionRetinal VesselsRoleRouget CellsSightSignal TransductionSignal Transduction SystemsSignalingSliceSolidStriate CortexStriate areaSymptomsTestingTherapeuticTimeTissuesTrainingUniversitiesVasodilatationVasodilationVasorelaxationVeinsVisionVisualVisual CortexVisual StimulationVisual SystemWorkWritingage dependent macular degenerationage induced macular degenerationage related macular diseaseage related macular dystrophyarea striataarteriolebehavior testbehavioral testbiological signal transductionblood vessels in the brainbrain blood vesselsbrain vasculaturecandidate identificationcapillarycareercareer developmentcerebral blood vesselcerebral vasculaturecerebrovascular vesselscerebrovasculatureclass developmentcourse developmentcourse material developmentdata basedegenerative diseases of motor and sensory neuronsdegenerative neurological diseasesdensitydetectordirect applicationelectrophysiologicalexperienceexperimentexperimental researchexperimental studyexperimentsextracellulareye disordergene manipulationgenetic manipulationgenetically manipulategenetically perturbglaucomatousimagingimprovedin vivoinnovateinnovationinnovativeinsightmedical collegemedical schoolsmeetingmeetingsmouse modelmulti-electrode arraysmultielectrode arraysmurine modelneuralneural degenerationneural dysfunctionneural functionneuro-vascularneuro-vascular couplingneurobiologicalneurodegenerationneurodegenerativeneurodegenerative illnessneurological degenerationneuronalneuronal degenerationneurovascularneurovascular abnormalityneurovascular couplingneurovascular dysregulationneurovascular impairmentneurovascular pathologyneurovasculopathynew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnovelnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetocular diseaseocular disorderophthalmopathypathophysiologypathwaypost-docpost-doctoralpost-doctoral traineepreparationsprimary degenerative dementiapublic health relevancereceptorresearch associatesresponseretina blood vessel structureretinal vascular networkretinal vascular structureretinal vasculatureschool of medicinesenile dementia of the Alzheimer typesenile macular diseaseskillssocial roletherapeutic targetthree dimensionaltooltwo-photonvascularvascular imagingvasculature Imagingvision lossvisual corticalvisual functionvisual loss
Description preview
PROJECT SUMMARY
Lujing Chen, Ph.D., is a neuroscientist whose ultimate career goal is to investigate neural and vascular
interactions in the visual system, with the aim of offering clinical insights to improve treatments of vision loss in
related diseases. The proposed research aims to develop powerful platforms to study the mechanisms
underlying…
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