grant
Neuromechanical Bases for the Increased Energy Cost of Walking in Aging
Organization UNIVERSITY OF MASSACHUSETTS AMHERSTLocation HADLEY, UNITED STATESPosted 15 Aug 2025Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY202521+ years oldAccelerometerAddressAdultAdult HumanAgeAgingAnkleAtrophicAtrophyBioenergeticsBiomechanicsCommunitiesConsensusCoxaDataDecline in mobilityDecrease in mobilityDecreased mobilityDiminished mobilityDistalDysfunctionEducational workshopElectromyographyExtensorFemaleFlexorFunctional disorderGaitGait AnalysisGasesGoalsHealthHipHip region structureHumanIndirect CalorimetryIsometric ContractionJointsKneeKnowledgeLiteratureMR ImagingMR SpectroscopyMR TomographyMRIMRIsMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMeasuresMechanicsMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMetabolicMethodsMobility declineMobility impairmentModern ManMotionMuscleMuscle AtrophyMuscle TissueMuscle WeaknessMuscular AtrophyMuscular WeaknessNIH RFANMR ImagingNMR TomographyNeuromechanicsNuclear Magnetic Resonance ImagingOutcomePhysical FunctionPhysical activityPhysiologicPhysiologicalPhysiopathologyPublic HealthQOLQuality of lifeReduced mobilityReduction in mobilityRegio tarsalisRequest for ApplicationsRespiration CalorimetryRoleTimeTorqueTranslatingWalkingWorkWork LoadWorkloadWorkshopZeugmatographyaccelerometryactivity monitoractivity trackeradulthoodage associatedage associated alterationsage associated changesage associated effectsage correlatedage correlated alterationsage correlated changesage dependentage dependent alterationsage dependent changesage effectage induced alterationsage induced changesage linkedage relatedage related alterationsage related changesage related effectsage specificage specific alterationsage specific changesaged groupaged groupsaged individualaged individualsaged peopleaged personaged personsaged populationaged populationsagesaging associated alterationsaging associated changesaging correlated alterationsaging correlated changesaging dependent alterationsaging dependent changesaging effectaging induced alterationsaging induced changesaging populationaging related alterationsaging related changesaging specific alterationsaging specific changesalterations with agebasebasesbiological sexbiological sex as a modifierbiomechanicalchanges with agecofactorcostexperiencegait examinationimpact of agein vivoinfluence of ageinterdisciplinary approachmalemechanicmechanicalmultidisciplinary approachmuscle breakdownmuscle degradationmuscle deteriorationmuscle lossmuscle strengthmuscle wastingmuscularneuralneuromechanicalneuromuscularnovelold ageolder adultolder adulthoodpathophysiologypopulation agingsexsex as a biological factorsex as a biological measuresex as a biological risk factorsex as a biological variablesex as a biological variancesex as a biologically significant variablesex as a fundamental variablesocial role♀♂
Description preview
PROJECT SUMMARY
Age-related mobility loss is a major public health concern due to its profound negative effect on health and
quality of life. An increased energetic cost to perform activities such as walking has been well-documented in
older adults and may be a primary contributor to age-related mobility loss. However, the mechanisms that
lead to…
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