grant
Narrow Band Green Light Effects on Cortical Excitability and Responsivity in Migraine
Organization BETH ISRAEL DEACONESS MEDICAL CENTERLocation BOSTON, UNITED STATESPosted 1 Aug 2023Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY2025ActinotherapyAcuteAffectAffectiveAmberAnalgesia TestsAnesthesiaAnesthesia proceduresAnimal Disease ModelsAnimal ModelAnimal Models and Related StudiesAnxietyAreaAttenuatedAurasAversive StimulusBasic ResearchBasic ScienceBrainBrain Nervous SystemCell Communication and SignalingCell SignalingCephalalgiaCephalgiaCephalodyniaCharacteristicsClinicalClinical DataClinical ResearchClinical SciencesClinical StudyCognitiveColorCommon Rat StrainsComplexCranial PainDarknessDataDevelopmentDiseaseDisorderElectrocorticogramElectrophysiologyElectrophysiology (science)EmotionalEncephalonEventExposure toFemaleFrequenciesGoalsHead PainHeadacheHourHumanIntracellular Communication and SignalingKnowledgeLeao depressionLightLight SensitivityLight TherapyLong-term painMeasuresMedialMethodsMigraineMigraine HeadacheModern ManNerve CellsNerve UnitNeural CellNeurobiologyNeurocyteNeuronsNeurophysiology / ElectrophysiologyNociceptionNociception TestsOut-patientsOutpatientsPainPain AssessmentPain MeasurementPain measurePainfulPatientsPersistent painPhotophobiaPhotoradiationPhotoradiation TherapyPhototherapyPropertyPublishingRatRats MammalsRattusResearchResearch DesignRestRiskRodent ModelSedation procedureSensorySeriesSignal TransductionSignal Transduction SystemsSignalingSomatosensory CortexSpecificitySpreading Cortical DepressionStimulusStudy TypeSymptomsTestingTherapeuticWorkanimal dataattenuateattenuatesawakebiological signal transductionconstant paindevelopmentalelectrocorticographyelectrophysiologicalexperiencefNIRSfrontal cortexfrontal lobefunctional near infrared spectroscopyhead achehuman subjectimaging spectroscopyinsightlasting painlight effectslight interventionlight treatmentmalemembermigraine therapymigraine treatmentmodel of animalneuralneurobiologicalneuronalnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynociceptivenovelnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachon-going painongoing painpain assaypain perceptionperceptual stimulusphysicochemical phenomena related to the sensesportabilitypre-clinical researchpre-clinical studypreclinical researchpreclinical studyresponsesedationsensory stimulusside effectsomesthetic sensory cortexspectroscopic imagingstudy designtranslational studytrend♀♂
Description preview
ABSTRACT
Significance: Exposure to narrow band green light (nbGL) appears to reduce intensity, frequency, and duration
of migraine headache and some of its most bothersome symptoms and does so more effectively than exposure to
dark. Because many migraine characteristics are attributed to abnormal cortical hyperexcitability and responsivity,
we are…
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