grant
NAFLD Diagnosis and Outcomes
Organization MAYO CLINIC ROCHESTERLocation ROCHESTER, UNITED STATESPosted 15 Feb 2024Deadline 31 Dec 2028
NIHUS FederalResearch GrantFY202621+ years oldAI algorithmAI basedAI based modelAI modelAI systemActive Follow-upAdultAdult HumanAffectAlgorithmsArtificial IntelligenceBiopsyCalibrationCaringCessation of lifeCirrhosisClinicalClinical PathsClinical PathwaysCommunitiesComputer ReasoningCountyDataData AnalyticsData BasesData ScienceData SetDatabasesDeathDiagnosisDiagnosticDiseaseDisease ManagementDisease OutcomeDisease ProgressionDisorderDisorder ManagementDrugsEHR systemEarly DiagnosisEarly identificationElectronic Health RecordEnrollmentEpidemiologyEvaluationEventFatsFatty acid glycerol estersFibrosisFutureGeneral PopulationGeneral PublicGoalsHealthHealth CareHepatic CancerHepatic DisorderHepatic TransplantationHepatologyHistoryIndividualInterventionLaboratoriesLeadLiverLiver GraftingLiver TransplantLiver diseasesLiver lesion biopsyMR ImagingMR TomographyMRIMRIsMachine IntelligenceMachine LearningMagnetic Resonance ImagingMalignant neoplasm of liverMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMedicationMethodsMinnesotaMissionModelingMorbidityNAFLDNASHNIDDKNMR ImagingNMR TomographyNational Institute of Diabetes and Digestive and Kidney DiseasesNuclear Magnetic Resonance ImagingOutcomePathway interactionsPatient SelectionPatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPatternPb elementPerformancePharmaceutical PreparationsPhenotypePopulationPopulation ResearchPopulation-based researchPopulation-level researchPrimary CareProcessProspective cohortPublic HealthRecording of previous eventsResearchRiskSeverity of illnessStatistical MethodsSteatohepatitisSymptomsSystemTestingTherapeutic InterventionTrainingValidationWorkZeugmatographyactive followupadulthoodartificial intelligence algorithmartificial intelligence basedartificial intelligence modelartificial intelligence-based modelcare resource usecare resource utilizationchronic hepatic diseasechronic hepatic disorderchronic liver diseasechronic liver disordercirrhoticclinical decision-makingclinical heterogeneityclinical phenotypeclinical practiceclinical significanceclinically significantcohortcompeting riskcomputer based predictiondata basedata integrationdeath riskdemographicsdisease controldisease diagnosisdisease phenotypedisease riskdisease severitydisorder controldisorder riskdrug/agentearly detectionelastic imagingelasticity imagingelastographyelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health record systemelectronic health registryelectronic medical health recordenrollepidemiologicepidemiologicalfollow upfollow-upfollowed upfollowuphealth care burdenhealth care resource usehealth care resource utilizationhealth care settingsheavy metal Pbheavy metal leadhepatic body systemhepatic diseasehepatic organ systemhepatopathyhistoriesimprovedinnovateinnovationinnovativeintervention therapyinvestigate populationliver biopsyliver cancerliver disorderliver malignancyliver transplantationmachine based learningmalignant liver tumormodel developmentmodel developmentsmortalitymortality riskmulti-modalitymultimodalitynon-alcohol fatty liver diseasenon-alcohol induced steatohepatitisnon-alcoholic fatty liver diseasenon-alcoholic liver diseasenon-alcoholic steato-hepatitisnon-alcoholic steatohepatitisnonalcoholic fatty liver diseasenonalcoholic steato-hepatitisnonalcoholic steatohepatitispathwaypatient oriented outcomespersonalized health interventionpersonalized interventionpopulation basedpopulation healthpopulation investigationpopulation level investigationpopulation specific researchprecision interventionspredictive modelingpreventpreventingprimary care practiceprophylacticprospectiverisk stratificationscreeningscreeningsstatistic methodsstratify riskstudies of populationsstudy of the populationstudy populationsurvey populationtoolvalidations
Description preview
PROJECT SUMMARY
Nonalcoholic fatty liver disease (NAFLD) affects 25-30% of US adults and has a major impact on healthcare
burden and population health due to higher morbidity and mortality than the general population. Even though
NAFLD can progress to cirrhosis, decompensation, and liver cancer, these outcomes affect a small proportion
of…
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