grant
Molecular Signal Integration for Root Growth Control
Organization SALK INSTITUTE FOR BIOLOGICAL STUDIESLocation La Jolla, UNITED STATESPosted 1 Aug 2018Deadline 31 Jan 2029
NIHUS FederalResearch GrantFY2026Active OxygenAllelesAllelomorphsArabidopsisArabidopsis thalianaAreaBasal Transcription FactorBasal transcription factor genesBindingBioavailabilityBiochemistryBiologic ModelsBiological AvailabilityBiological ChemistryBiological ModelsBody TissuesCancersCandidate Disease GeneCandidate GeneCell BodyCell Communication and SignalingCell SignalingCellsCellular ExpansionCellular GrowthComplexCuesDNA Molecular BiologyDataDiseaseDisorderEndocytosisFe elementFlagellinGWA studyGWASGene variantGeneral Transcription Factor GeneGeneral Transcription FactorsGeneralized GrowthGenesGeneticGenetic DiversityGenetic VariationGenetic studyGenomicsGenotypeGrowthGrowth and DevelopmentGrowth and Development functionHealthHydrogen OxideImmunityIndividualInfectionIntracellular Communication and SignalingIronKinasesLigandsMalignant NeoplasmsMalignant TumorMammaliaMammalsMeasuresMediatingMicroscopyModel SystemModelingMolecularMolecular BiologyMolecular InteractionMonitorMouse-ear CressNucleic Acid Regulator RegionsNucleic Acid Regulatory SequencesNutrientOrganOrganismOther GeneticsOutputOxidation-ReductionOxygen RadicalsPathway interactionsPatientsPatternPerceptionPhenotypePhosphorylationPhosphotransferase GenePhosphotransferasesPhysiologic AvailabilityPlant ModelPlant RootsPlantsPredictive FactorPro-OxidantsProcessProtein PhosphorylationReactionReactive Oxygen SpeciesReceptor ProteinRedoxRegulationRegulatory PathwayRegulatory RegionsReproducibilityResearchRoleShapesSignal TransductionSignal Transduction SystemsSignalingSoilStructureSystemTestingTimeTissue GrowthTissuesTranscription Factor Proto-OncogeneTranscription factor genesTransphosphorylasesUbiquitilationUbiquitinationUbiquitinoylationWaterallelic variantbasebasesbiological signal transductioncell growthdefense responsedesigndesigningexperimentexperimental researchexperimental studyexperimentsextracellularfitnessgenetic approachgenetic regulatory elementgenetic strategygenetic variantgenome wide associationgenome wide association scangenome wide association studygenomewide association scangenomewide association studygenomic variantinsightlife spanlifespanliving systemmalignancymicrobialneoplasm/cancernon-invasive imagingnoninvasive imagingontogenyorgan developmentorgan growthoxidation reduction reactionpathogenpathwaypersonalization of treatmentpersonalized medicinepersonalized therapypersonalized treatmentphenomicsphysiological defense responsepromoterpromotorreceptorresponsesocial roletranscription factorubiquinationubiquitin conjugationwhole genome association analysiswhole genome association study
Description preview
PROJECT SUMMARY
Multicellular organisms must precisely control the growth and size of tissues and organs. For this, cells
reproducibly and accurately interpret information conveyed by extrinsic signals and perceived by a large array
of sensing machinery. Malfunction of these growth-regulatory pathways decreases organismal fitness and can
lead to…
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