grant
Molecular Mechanisms of Sugar Sensing by Insect Gustatory Receptors
NIHUS FederalResearch GrantFY2025AffectAfferent NeuronsAmino AcidsAnimalsAssayBindingBioassayBiological AssayBiophysicsBombyx moriCationsCell BodyCellsCessation of lifeChemicalsChemoreceptorsCognitive DiscriminationCollectionComplexCoupledCouplesCuesCulicidaeD-GlucoseDataDeathDetectionDextroseDisaccharidesDiscriminationDockingDrosophila gustatory receptorEsthesiaFamilyFoundationsFructoseGenetics-MutagenesisGlucoseGustationHealth FoodHexosesHumanIn VitroInsect BitesInsect VectorsInsectaInsectsInsects InvertebratesIon ChannelIonic ChannelsIonsLevuloseLifeLigand BindingLigandsLinkMembrane ChannelsMetabolicMethodsModelingModern ManMolecularMolecular InteractionMosquitoesMothsMutagenesisMutagenesis Molecular BiologyNutritious foodOutcomePatternPersonsPoisonPotential EnergyReceptor ProteinRoleRouteSaccharoseSensationSensory NeuronsSideSilkSpecificityStructureSucroseTasteTaste BudsTaste PerceptionToxic ChemicalToxic SubstanceTrehaloseaminoacidanalogantagonismantagonistbasebasesbiophysical foundationbiophysical principlesbiophysical scienceschemical groupdesigndesigningdetection of nutrientexperimentexperimental researchexperimental studyexperimentsgustatory perceptiongustatory processinggustatory responsegustatory systemhealthy foodhuman pathogennovelnutrient sensingpathogenperception of nutrientsreceptorreceptor bindingreceptor boundresponsesmall moleculesocial rolestructural biologysugarsweet tastesweet taste perceptiontaste processingtaste receptortaste responsetaste systemtooltoxic compound
Description preview
PROJECT SUMMARY
Animals desire sugars for their energy potential and for the pleasurable sensation of tasting sweetness. Despite
the importance of sugar receptors in influencing nutrient sensing, metabolic responses, and taste perception,
few studies have been performed to identify the molecular mechanisms underlying sugar detection and…
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