grant
Molecular Mechanisms of Filoviral-host Interactions
Organization WASHINGTON UNIVERSITYLocation SAINT LOUIS, UNITED STATESPosted 7 Jul 2016Deadline 31 May 2028
NIHUS FederalResearch GrantFY2025AcademiaActinsAddressAntibodiesAntibody TherapyAssayBioassayBiochemicalBiochemistryBiologicalBiological AssayBiological ChemistryBiologyCRISPRCRISPR/Cas systemCell BodyCell Culture TechniquesCell LineCellLineCellsCellular biologyClustered Regularly Interspaced Short Palindromic RepeatsCollaborationsComplexComputer AssistedContainmentCryo-electron MicroscopyCryoelectron MicroscopyDNA mutationDataDevelopmentDiseaseDisease OutbreaksDisorderDistantEBOVEbola virusEbola-like VirusesElectron CryomicroscopyEmerging Communicable DiseasesEmerging Infectious DiseasesEnsureEvaluationFamilyFamily memberFiloviridaeFiloviridae InfectionsFilovirusFrankfurt-Marburg Syndrome VirusFundingGene TranscriptionGeneralized GrowthGeneticGenetic ChangeGenetic TranscriptionGenetic defectGenetic mutationGoalsGrowthHLA-DR Associated Protein IIHost FactorHost Factor ProteinIGAADImmune responseImmunologyIndustryInfectionInhibitor of GZMA-Activated DNaseIntegration Host FactorsInvestigatorsKO miceKnock-out MiceKnockout MiceKnowledgeLaboratoriesLearningMapsMarburgMarburg Virus DiseaseMarburg hemorrhagic feverMarburg virusMarburg-like VirusesMarburgvirusMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMethodsModelingMolecularMutationNetwork AnalysisNucleocapsidNull MouseOrthoebolavirusOrthomarburgvirusOutbreaksP01 MechanismP01 ProgramPathogenesisPathway AnalysisPathway interactionsPeriodicalsPhenotypePhosphatase 2A Inhibitor I2PP2APhysical condensationPlayPredispositionProductivityProgram Project GrantProgram Research Project GrantsProgress ReportsProtein Interaction MapProtein-Protein Interaction MapProteinsProteomicsPublic HealthPublicationsR-Series Research ProjectsR01 MechanismR01 ProgramRNA ExpressionRNA ProcessingReagentRecordsResearchResearch GrantsResearch PersonnelResearch Program ProjectsResearch Project GrantsResearch ProjectsResearch ResourcesResearchersResource SharingResourcesRodentRodentiaRodents MammalsRoleSET Translocation Inhibitor-2 of Protein Phosphatase-2AScientific PublicationScientistSet proteinStrains Cell LinesSusceptibilitySystemTemplate Activating Factor I BetaTestingTherapeuticTherapeutic InterventionTissue GrowthTranscriptionTransgenic OrganismsVaccinesViralViral DiseasesViral Gene ProductsViral Gene ProteinsViral ProteinsVirionVirusVirus AssemblyVirus DiseasesVirus ParticleVirus ReplicationVirus-like particleWorkZoonosesZoonoticZoonotic Infectionantibody based therapiesantibody treatmentantibody-based therapeuticsantibody-based treatmentbiologiccell biologycell culturecell culturescell typecomputer aidedcondensationconditional knock-outconditional knockoutcryo-EMcryoEMcryogenic electron microscopycultured cell linedata complexitydata sharingdevelopmentalemerging pathogenexperiencefilovirus infectionsgenome mutationhost responsehuman diseaseimmune system responseimmunoresponsein vivoinnovateinnovationinnovativeinsightinterdisciplinary approachintervention therapymedical countermeasuremouse modelmultidisciplinary approachmurine modelnew drug targetnew druggable targetnew pathogennew pharmacotherapy targetnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapeutic targetnew therapy approachesnew therapy targetnew treatment approachnew treatment strategynovelnovel drug targetnovel druggable targetnovel pathogennovel pharmacotherapy targetnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapeutic targetnovel therapy approachnovel therapy targetontogenypathogenpathwayperiodicperiodicalprotein protein interactionrecruitsocial rolestructural biologytargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttomographytraining opportunitytransgenicviral assemblyviral infectionviral multiplicationviral replicationvirologyvirus infectionvirus multiplicationvirus proteinvirus-induced diseasevirus-like nanoparticlesviruslike particle
Description preview
Overall Project Summary/Abstract: Molecular mechanisms of filoviral-host interactions
The family Filoviridae, which includes Ebola virus (EBOV) and Marburg virus (MARV), are zoonotic pathogens
that cause outbreaks of severe human disease and require biosafety level 4 (BSL4) containment for study.
Recent approval of a vaccine and antibody-based…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click