grant

Molecular interactions required for targeting mRNA to nonsense-mediated decay.

Organization Case Western Reserve UniversityLocation CLEVELAND, United StatesPosted 1 Sept 2025Deadline 31 Aug 2028
NSFUS FederalResearch GrantScience FoundationOH
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Description preview

Cells have evolved sophisticated strategies to ensure the accurate expression of genetic information and safeguard against potentially harmful effects of defective messenger RNA (mRNA) and proteins. One such strategy recognizes mRNA translation events that terminate prematurely and targets the faulty mRNA transcript for rapid degradation. This…

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Molecular interactions required for targeting mRNA to nonsense-mediated decay. — Case Western Reserve University | Unite | Dev Procure