grant
Molecular Genetics and Cell Biology of Pathogenic Spirochetes
Organization NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESLocation UNITED STATES
NIHUS FederalResearch GrantFY2025B burgdorferiB. burgdorferiBacteriaBacterial InfectionsBiologicalBorrelia burgdorferiBorrelia burgdorferi sensu strictoBorreliella burgdorferiCell FunctionCell PhysiologyCell ProcessCellular FunctionCellular PhysiologyCellular ProcessCellular biologyEmerging Communicable DiseasesEmerging Infectious DiseasesEnvironmentGene Action RegulationGene ExpressionGene Expression RegulationGene RegulationGene Regulation ProcessGenesGoalsImmune responseInfectionIxodidaLyme BorreliosisLyme DiseaseLyme Disease SpirocheteMapsMolecularMolecular GeneticsOrder SpirochaetalesPathogenicityResearchSourceSpirochaetalesSpirochetesSubcellular ProcessTechniquesTemperatureTicksWorkbacteria infectionbacterial diseasebiologiccell biologygene regulatory networkglobal gene expressionglobal transcription profilehost responseimmune system responseimmunoresponselyme spirochetetranscriptomevector-bornevectorborne
Description preview
In FY2025, our work has focused on characterizing principles of cell biology and gene regulation in the Lyme disease spirochete, B. burgdorferi. Lyme disease is an emerging infectious disease and the foremost vector-borne bacterial infection in the world. B. burgdorferi inhabits tick and mammalian hosts, environments with very different…
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