grant
Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder using Transcranial Magnetic Stimulation
NIHUS FederalResearch GrantFY202521+ years oldASDAdultAdult HumanAffectAgeAreaAutismAutistic DisorderBehaviorBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioral Conditioning TherapyBehavioral ModificationBehavioral TherapyBehavioral TreatmentBilateralBrainBrain Nervous SystemBrain regionCharacteristicsClinical ResearchClinical StudyConditioning TherapyDataDiagnosisDouble-Blind MethodDouble-Blind StudyDouble-BlindedDouble-Masked MethodDouble-Masked StudyEarly Infantile AutismEmotionsEncephalonFunctional MRIFunctional Magnetic Resonance ImagingFutureHigh PrevalenceImpairmentIndividualInfantile AutismInvestigationKanner's SyndromeLeftLifeMRI ScansMagnetic Resonance Imaging ScanMedialMethodsMindModelingMotivationParticipantPatient Self-ReportPatientsPrefrontal CortexProcessPublishingReportingResearchRestRoleSamplingScanningScheduleSchizophreniaSchizophrenic DisordersSelf-ReportSocial BehaviorSocial InteractionStructure of superior temporal sulcusSuperior Temporal SulcusSymptomsTranscranial magnetic stimulationTreatment Efficacyadult with ASDadult with autismadult with autism spectrum disorderadult youthadulthoodadults on the autism spectrumadults on the spectrumagesassess effectivenessautism spectral disorderautism spectrum disorderautistic adultautistic individualsautistic peopleautistic spectrum disorderbehavior interventionbehavioral interventioncingulate cortexcognitive processdementia praecoxdesigndesigningdetermine effectivenesseffective interventioneffectiveness assessmenteffectiveness evaluationelectric fieldevaluate effectivenessexamine effectivenessfMRIfMRI scanfunctional MRI scanfunctional magnetic resonance imaging scanindividuals on the autism spectrumindividuals on the spectrumindividuals with ASDindividuals with autismindividuals with autism spectrum disorderintervention efficacymental representationmentalizationneuralneural circuitneural circuitryneural mechanismneural networkneurocircuitryneuromechanismnon-invasive brain stimulationpeople on the autism spectrumpeople with ASDpeople with autismpeople with autism spectrum disorderrecruitrepetitive transcranial magnetic stimulationschizophrenicside effectskillssocialsocial cognitionsocial communicationsocial defectssocial deficitssocial disorderssocial dysfunctionsocial rolesociobehaviorsociobehavioralsuccesssynaptic circuitsynaptic circuitrytheory of mindtherapeutic efficacytherapy efficacyyoung adultyoung adult ageyoung adulthood
Description preview
Deficits in mentalizing, a high-order social cognitive process that allows individuals to build representations of
others’ state of mind (e.g. emotions and motivation) and adjust their own behaviors accordingly, are
hypothesized to underline the core social communication abnormalities that characterize autism spectrum
disorder (ASD). Our pilot…
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