grant

Methods for Epidemiology Studies

Organization DIVISION OF CANCER EPIDEMIOLOGY AND GENETICSLocation UNITED STATES
NIHUS FederalResearch GrantFY2025AddressAreaBiological MarkersBiometricsBiometryBiostatisticsBloodBlood Reticuloendothelial SystemBreastBreast CancerBreast Cancer DetectionBreast Cancer EducationBreast cancer screeningBreast screeningBronchiCalibrationCancer DetectionCategoriesCervical Cancer ScreeningColonColorectal CancerComplexComputer softwareDCEGDataData AnalysesData AnalysisDifferential Algebraic EquationDifferential EquationDiseaseDisorderDivision of Cancer Epidemiology and GeneticsDoseElectronic Health RecordEnvironmental FactorEnvironmental Risk FactorEpidemiologic MethodologyEpidemiologic MethodsEpidemiologic ResearchEpidemiologic StudiesEpidemiologic research methodologyEpidemiologic research methodsEpidemiological MethodsEpidemiological StudiesEpidemiological TechniquesEpidemiology ResearchEquilibriumFamilyGene variantGenesGeneticGenetic MarkersGenomicsGenotypeHouseholdIndividualInternationalLeftLungLung Respiratory SystemMalignant Breast NeoplasmMalignant Tumor of the LungMalignant neoplasm of lungMeasurementMethodsMethods EpidemiologyMethods in epidemiologyMissionModelingNHANESNational Health and Nutrition Examination SurveyNetwork AnalysisObservational epidemiologyOutcomePLRAPathway AnalysisPleuraPleural TissueProceduresPulmonary CancerPulmonary malignant NeoplasmRectumResearchRiskRisk EstimateSamplingSeasonsSoftwareSurvey InstrumentSurveysTCGATestingThe Cancer Genome AtlasTracheaTrachea ProperVIT DVitamin Dallelic variantbalancebalance functionbeta diversitybio-markersbiologic markerbiomarkercervical cancer early detectioncervical screeningdata interpretationdesigndesigningdetection limitdimension reductiondimensionality reductiondisease riskdisorder riskelectronic health care recordelectronic health dataelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordenvironmental riskepidemiologic investigationepidemiology studygene biomarkergene expression biomarkergene markergene signature biomarkergenetic biomarkergenetic variantgenomic variantimprovedlung cancermalignant breast tumormammary cancer detectionmammary screeningmembermethod developmentmicrobiomenew approachesnovelnovel approachesnovel strategiesnovel strategypopulation basedprecancer cervical detectionprotective effectrecommended screeningreduce data dimensionreduce dimensionalityresponsescreening guidelinesscreening recommendationssemiparametricstatisticstraitwindpipe
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Extensions of likelihood-based sufficient dimension reduction methods were proposed and studied for analyzing biomarkers that are left and/or right censored due to lower or upper limits of detection. These methods apply generally to any type of outcome, including continuous and categorical outcomes. Bias of estimates of exposure effects…

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