grant
Memory guided planning across the lifespan
Organization UNIVERSITY OF CALIFORNIA-IRVINELocation IRVINE, UNITED STATESPosted 15 May 2025Deadline 30 Apr 2030
NIHUS FederalResearch GrantFY2025AD related dementiaADRDAddressAffectAgeAge associated cognitive deficitAge associated cognitive dysfunctionAge related memory declineAge related memory deficitAge related memory impairmentAge-associated cognitive declineAge-related cognitive declineAgingAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaBehaviorBehavioralBenign senescent forgetfulnessBrainBrain Nervous SystemChoice BehaviorCognitiveCognitive DiscriminationComplexComputer ModelsComputerized ModelsCorpus StriatumCorpus striatum structureDWI (diffusion weighted imaging)DWI-MRIDecision MakingDevelopmentDiagnosisDiffusionDiffusion MRIDiffusion Magnetic Resonance ImagingDiffusion Weighted MRIDiffusion weighted imagingDiffusion-weighted Magnetic Resonance ImagingDiscriminationDiseaseDisorderEarly identificationEducation for InterventionEducational InterventionEncephalonEnvironmentEpisodic memoryFailureFunctional MRIFunctional Magnetic Resonance ImagingFutureGoalsHealthHumanImpairmentIndividualInstruction InterventionInterventionInvestigatorsLeadLearningLifeLife InsuranceMeasuresMedialMedicalMemoryMemory LossModelingModern ManNeurobiologyOlder PopulationOutcomeParticipantPb elementPerformancePopulationProcessPsychological reinforcementReinforcementResearchResearch PersonnelResearchersRewardsRoleSpecificityStimulusStriate BodyStriatumStructureTemporal LobeTestingTrainingTraining InterventionVariantVariationWorkadult youthage associatedage associated biomarkersage associated cognitive impairmentage associated declineage associated differenceage associated diseaseage associated disorderage associated effectsage associated impairmentage associated markerage associated memory declineage associated memory deficitage based differenceage correlatedage dependentage dependent declineage dependent differenceage dependent diseaseage dependent disorderage dependent impairmentage dependent variationage differenceage effectage linkedage markerage relatedage related biomarkersage related cognitive deficitage related cognitive dysfunctionage related cognitive impairmentage related declineage related differenceage related effectsage related human diseaseage related markersage related memory dysfunctionage related variationage specificage specific differenceage-associated memory impairmentage-induced cognitive declineage-related decline in cognitionage-related decline in cognitive functionage-related diseaseage-related disorderage-related impairmentagesaging effectaging related cognitive declinebehavior studybehavioral studybiological markers of agebiomarkers of agecomputational frameworkcomputational modelingcomputational modelscomputer based modelscomputer frameworkcomputerized modelingdMRIdecline with agedesigndesigningdevelopmentaldiffer by agedifference across agedifference in agediffuseddiffusesdiffusingdiffusion tensor imagingdiffusionsexamination questionsexperiencefMRIflexibilityflexibleheavy metal Pbheavy metal leadimage-based methodimaging methodimaging modalityimpact of ageimprovedinfluence of ageinstructional interventioninsurance planintervention designlearning outcomelife spanlifespanmemory declinemulti-modalitymultimodalitynatural agingneuralneural circuitneural circuitryneural imagingneuro-imagingneurobiologicalneurocircuitryneuroimagingneurological imagingnormal agingnormative agingnovelolder adultolder adulthoodolder groupsolder individualsolder personreward processingsocial rolestatistical learningstriatalsuccesssynaptic circuitsynaptic circuitrytemporal cortextherapy designtreatment designvariation by ageyoung adultyoung adult ageyoung adulthood
Description preview
PROJECT SUMMARY
Throughout life, we routinely make decisions that impact our physical and financial health (e.g., which life
insurance plan to choose or whether to get a medical treatment). Our ability to make appropriate future
decisions depend, at least in part, on accurate memory for past choices, including memory for the context in
which those…
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