grant
Medicinal Chemistry Core
Organization HACKENSACK UNIVERSITY MEDICAL CENTERLocation HACKENSACK, UNITED STATESPosted 20 Jun 2025Deadline 31 May 2030
NIHUS FederalResearch GrantFY2025AccelerationAddressAnimal ModelAnimal Models and Related StudiesAnti-Bacterial AgentsBacterial Drug ResistanceBacterial InfectionsBiotechBiotechnologyCenters for Disease ControlCenters for Disease Control and PreventionCenters for Disease Control and Prevention (U.S.)ChemicalsChemistryClinicalCommunicationCompetenceCrystallizationDataDevelopmentDoctor of PhilosophyDrug IndustryDrug KineticsDrug resistanceDrugsFormulationGrantHuman ResourcesIndazolesIndividualIndustrializationIndustryIndustry StandardInfectionInvestigatorsLeadLeadershipLearningLogisticsM abscessusM. abscessusManpowerMedicationMedicinal ChemistryMicrobiologyMolecularMolecular MachinesMolecular Modeling Nucleic Acid BiochemistryMolecular Modeling Protein/Amino Acid BiochemistryMolecular ModelsMycobacterium Avium InfectionMycobacterium abscessusMycobacterium avium-intracellulare InfectionMycobacterium intracellulare InfectionMycobacteroides abscessusPb elementPh.D.PhDPharmaceutic ChemistryPharmaceutic IndustryPharmaceutical AgentPharmaceutical ChemistryPharmaceutical IndustryPharmaceutical PreparationsPharmaceuticalsPharmacokineticsPharmacologic SubstancePharmacological SubstancePharmacologyPhasePostdocPostdoctoral FellowPropertyPublicationsPublishingResearchResearch AssociateResearch PersonnelResearch ResourcesResearchersResourcesRifamycinsS aureusS epidermidisS. aureusS. epidermidisScientific PublicationSeriesSightSodium ChlorideSolubilityStaph aureusStaphylococcus aureusStaphylococcus epidermidisStructureStructure-Activity RelationshipSulfonamidesSynthesis ChemistrySynthetic ChemistryTechniquesToxic effectToxicitiesToxicologyTranslationsUnited States Centers for Disease ControlUnited States Centers for Disease Control and PreventionVisionWorkWorld Health Organizationanaloganti-bacterialanti-bacterial drug resistanceanti-bacterial drug resistantanti-bacterial resistanceanti-bacterial resistantbacteria infectionbacterial diseasebeta lactam antibioticbeta-Lactamscandidate selectionchemical informaticschemical structure functioncheminformaticsdesigndesigningdevelopmentaldrug candidatedrug developmentdrug discoverydrug resistantdrug/agentefficacy studyexperiencegenotoxicityglobal healthheavy metal Pbheavy metal leadinsightlead optimizationmachine learning based methodmachine learning based modelmachine learning methodmachine learning methodologiesmachine learning modelmembermodel of animalmolecular modelingnovelpersonnelpharmaceuticalpost-docpost-doctoralpost-doctoral traineepre-clinical developmentpreclinical developmentprocess optimizationprogramsresearch associatesresistance to Drugresistance to anti-bacterialresistant to Drugresistant to anti-bacterialsaltscale upscreeningscreeningssmall moleculestructure function relationshiptranslationvisual functionβ lactam antibioticβ-Lactams
Description preview
SUMMARY
The Medicinal Chemistry Core (MCC) will provide synthetic and medicinal chemistry, cheminformatics, and
structure-based design resources complementary to those existing within the respective project teams. It will
integrate tightly with the other Cores. The MCC resource will distinguish itself by relying on extensive
pharmaceutical…
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