grant
Mechanisms of neural circuit dynamics in working memory and decision-making
Organization PRINCETON UNIVERSITYLocation Princeton, UNITED STATESPosted 8 Aug 2023Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AD dementiaAD/HDADHDASDAddressAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimers DementiaAmentiaAmmon HornAnatomic SitesAnatomic structuresAnatomyAnimalsArchitectureAreaArousalAssayAttention deficit hyperactivity disorderAutismAutistic DisorderBRAIN initiativeBasic ResearchBasic ScienceBehaviorBehavioralBehavioral ParadigmBioassayBiological AssayBipolar DepressionBrainBrain Nervous SystemBrain Research through Advancing Innovative Neurotechnologies initiativeBrain regionCausalityCognitiveComputer ModelsComputerized ModelsCornu AmmonisDataDecision MakingDementiaDevelopmentEarly Infantile AutismElectron MicroscopyElectrophysiologyElectrophysiology (science)EncephalonEngineering / ArchitectureEtiologyExhibitsFamilyGeometryGoalsHippocampusHungerImageImmediate MemoryIndividualInfantile AutismInvestigatorsJointsKanner's SyndromeLinkMapsMental disordersMental health disordersMethodsMiceMice MammalsModelingModernizationMurineMusNeocortexNerve CellsNerve UnitNeural CellNeurocyteNeuronsNeurophysiology / ElectrophysiologyNeurosciencesPerformancePhysiologicPhysiologicalPositionPositioning AttributePredominantly Hyperactive-Impulsive Type Attention-Deficit DisorderPredominantly Hyperactive-Impulsive Type Hyperactivity DisorderPrimary Senile Degenerative DementiaPsychiatric DiseasePsychiatric DisorderResearchResearch PersonnelResearchersResolutionRodentRodentiaRodents MammalsRoleRunningSchizophreniaSchizophrenic DisordersSeriesShort-Term MemorySi elementSideSiliconStatistical MethodsStructureSystemTask PerformancesTechnologyTestingTherapeuticThirstTimeTransmission Electron MicroscopyVariantVariationWorkautism spectral disorderautism spectrum disorderautistic spectrum disorderbipolar depressedcausationcognitive abilitycognitive processcomputational modelingcomputational modelscomputational studiescomputer based modelscomputer studiescomputerized modelingdementia praecoxdevelopmentaldisease causationelectrophysiologicalexperimentexperimental researchexperimental studyexperimentshippocampalhomotypical corteximagingisocortexmembermental illnessneocorticalneopalliumneuralneural circuitneural circuitryneural mechanismneurocircuitryneuromechanismneuronalnext generationnoveloperationoperationspopulation basedprimary degenerative dementiaprogramspsychiatric illnesspsychological disorderresolutionsscaffoldscaffoldingschizophrenicsenile dementia of the Alzheimer typesocial rolestatistic methodssynaptic circuitsynaptic circuitryvirtual realityworking memory
Description preview
Project Summary/Abstract: Overall
The overarching goal of this U19 program is to determine how neural computations across brain regions
produce two core cognitive processes, working memory and decision-making, and thus to derive fundamental
principles of brain function. This renewal application proposes to pursue powerful new themes that emerged…
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