grant
MECHANISMS OF CONTRACTILE NETWORK ASSEMBLY
Organization LOYOLA UNIVERSITY CHICAGOLocation MAYWOOD, UNITED STATESPosted 1 Sept 2020Deadline 31 Aug 2030
NIHUS FederalResearch GrantFY2025Actin-Activated ATPaseAutoregulationBody TissuesCell BodyCell FunctionCell PhysiologyCell ProcessCellsCellular FunctionCellular PhysiologyCellular ProcessCellular biologyDevelopmental BiologyEventFilamentGoalsHeavy Meromyosin Subfragment-2HomeostasisImaging ProceduresImaging TechnicsImaging TechniquesMammalian CellMechanicsMicroscopyMolecularMorphogenesisMotorMovementMyosin ATPaseMyosin Adenosine TriphosphataseMyosin AdenosinetriphosphataseMyosin S-2Myosin Subfragment-2MyosinsPhysiological HomeostasisProcessProteinsSubcellular ProcessTechniquesTimeTissuesWorkbody movementcell biologyinsightmechanicmechanicalmolecular arraymorphogenetic processprotein function
Description preview
Project Summary/Abstract
A fundamental question in cell physiology is how appropriate levels of cell contractility are
generated to drive cell and tissue morphogenesis and mechanical homeostasis. We know cells
contractile events to enable dynamic movements. We do not know how they generate and tune
contractility in the right place at the right…
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