grant
MDMA as a Treatment for Social Deficits in Schizophrenia
Organization UNIVERSITY OF CALIFORNIA LOS ANGELESLocation LOS ANGELES, UNITED STATESPosted 21 Sept 2023Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY20253,4 methylenedioxymethamphetamineActive Follow-upAcuteAddressAmphetaminesAntipsychotic AgentsAntipsychotic DrugsAntipsychoticsAttentionBehavioralBiologic PsychiatryBiological PsychiatryBiostatistics CoreBlood PlasmaCaliforniaCenter for Translational Science ActivitiesClinicalClinical TrialsCross-Over DesignsCrossover DesignCuesDelusionsDepartment chairDesoxynorephedrinDoseDrugsEmpathyEndocrine Gland SecretionFacultyFeelingFoundationsFunctional impairmentFundingFutureGoalsGrantHallucinationsHormonesHourHumanImpairmentIndividualInstitutionInterventionInvestigationInvestigatorsJournalsLaboratoriesLeadLos AngelesMDMAMagazineMajor TranquilizersMajor Tranquilizing AgentsMeasuresMedicationMental disordersMental health disordersMentorshipMethodologyMethylenedioxymethamphetamineModern ManMotivationN,alpha-dimethyl-1,3-benzodioxole-5-ethanamineN-Methyl-3,4-methylenedioxyamphetamineNeuroleptic AgentsNeuroleptic DrugsNeurolepticsOcytocinOxytocinPTSDPaperParticipantPatient Self-ReportPatientsPb elementPharmaceutical PreparationsPhasePhenaminePhenoprominPlacebosPlasmaPlasma SerumPopulationPositionPositioning AttributePost-Traumatic NeurosesPost-Traumatic Stress DisordersPosttraumatic NeurosesPropertyPsychiatric DiseasePsychiatric DisorderPsychiatryPsychoactive AgentsPsychoactive CompoundPsychoactive DrugsPsychopharmaceuticalsPsychopharmacologyPsychotropic DrugsPublicationsPublishingRecombinant OxytocinRegulatory approvalResearchResearch DesignResearch PersonnelResearchersReticuloendothelial System, Serum, PlasmaScheduleSchizophreniaSchizophrenic DisordersScienceScientific PublicationSecondary toSecureSelf-ReportSham TreatmentSocial FunctioningSocial disabilitySpeechStudy TypeSymptomsTestingTherapeuticTherapeutic HormoneTimeUniversitiesWorkactive followupattentional biasbehavioral pharmacologybiobehaviorbiobehavioraldata managementdebilitating symptomdementia praecoxdl-Amphetaminedrug/agentecstasyeffective therapyeffective treatmentexperiencefaculty mentorfeelingsfollow upfollow-upfollowed upfollowupfull professorfunction sociallyfunctioning socialhealthy volunteerheavy metal Pbheavy metal leadindexinginnovateinnovationinnovativemeetingmeetingsmental illnessneuropsychiatricneuropsychiatryneuropsychopharmacologynovelopen labelopen label studypatient populationpharmacobehavioralpharmacologicpost-trauma stress disorderposttrauma stress disorderprofessorprogramspsychiatric illnesspsychological disorderpsychopharmacologicpsychopharmacologicalpsychosocialpsychostimulantpsychotic symptomsrandomized placebo control trialrandomized placebo controlled trialregulatory authorizationregulatory certificationregulatory clearanceschizophrenicsenior facultysham therapysocialsocial attachmentsocial attentionsocial bondingsocial defectssocial deficitssocial disorderssocial dysfunctionsocial engagementsocial involvementsocial participationstudy designsymptom treatmentsymptomatic treatmenttranslational research centertranslational sciences centertraumatic neurosistreat symptom
Description preview
Project Summary/Abstract
Impaired social motivation, or “asociality,” is a negative symptom of schizophrenia and a cause of significant
functional impairment in the illness. Whereas many symptoms of schizophrenia can be treated with
antipsychotic medications, deficits in social motivation persist, leading to significant social disability in…
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