Matrix uptake driven reprogramming of pancreatic ductal adenocarcinoma (PDAC) metabolism
Description preview
Pancreatic ductal adenocarcinoma (PDAC) has one of the highest mortality rates of all cancers. PDAC is characterised by its stiff and dense extracellular matrix encapsulating the tumour and changes in metabolism that are required for survival in this environment. The stiff matrix promotes tumour growth and metastatic spread, alters immune cell…
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