grant
Mathematical modeling of mechanical and spatiotemporal processes in cellular functions
Organization VIRGINIA POLYTECHNIC INST AND ST UNIVLocation BLACKSBURG, UNITED STATESPosted 1 Sept 2020Deadline 28 Feb 2031
NIHUS FederalResearch GrantFY2026AddressAreaBacteriaBiologic ModelsBiologicalBiological ModelsBody TissuesC perfringensC welchiiC. perfringensC. welchiiCancer TreatmentCancersCell BodyCell Communication and SignalingCell FunctionCell PhysiologyCell ProcessCell SignalingCellsCellular FunctionCellular PhysiologyCellular ProcessCentrosomeChemistryChromosome SegregationClonal EvolutionClostridium perfringensClostridium welchiiComplexDataDevelopmentElementsFutureGeneralized GrowthGenerationsGrowthHealthIntracellular Communication and SignalingKnowledgeLaboratoriesLawsM PhaseMalignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorMath ModelsMechanicsMediatingMitosisMitosis StageMitotic spindleModel SystemModelingMolecularMotilityOutcomePenetrationPhysicsProcessRegulationResearchRoleSignal TransductionSignal Transduction SystemsSignalingSlideSubcellular ProcessTechniquesTissue GrowthTissuesUncertaintyWorkanti-cancer therapybiologicbiological signal transductioncancer therapycancer-directed therapychromosome divisioncopingdata heterogeneitydata set heterogeneitydataset heterogeneitydevelopmentaldoubtexperimentexperimental researchexperimental studyexperimentsheterogeneous dataheterogeneous data setsheterogeneous datasetsheterogenous dataheterogenous data setsheterogenous datasetsinnovateinnovationinnovativeinsightmalignancymathematic modelmathematical modelmathematical modelingmechanicmechanicalmechanical propertiesneoplasm/cancernovelontogenypredictive toolssocial rolespatial and temporalspatial temporalspatiotemporalsuccesstargeted cancer therapytool
Description preview
Project Summary
The PI’s laboratory focuses on mathematical modeling of mechanical and spatiotemporal processes in cellular
functions. Experiment data on these processes tend to be fragmented, as it remains challenging to
simultaneously track the mechanical and spatiotemporal dynamics of multiple molecular species involved in
complex cellular…
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