grant
Mapping the landscape of Fc gamma receptor expression in multiple myeloma (MM) to optimize IgG tumour targeting antibodies
Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
Description preview
Background:
MM is an incurable and common BM cancer. Monoclonal antibodies (mAbs) are a mainstay of treatment in MM and their MoA are Fc mediated. In other hematological and non-hematological malignancies, the expression and distribution of FcyR expression has been directly linked to the efficacy of tumour targeting IgG antibodies. However there…
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