grant
Manipulating the mitochondrial genome to investigate the impact of mtDNA mutations in cancer
Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
Description preview
Mutations of mtDNA are present in ~60% of all tumours and have long been overlooked in cancer biology. Recent groundbreaking work from my lab has identified mtDNA mutations as a major phenotype-modifier across all cancers, and mtDNA mutations in colorectal cancer were linked to major extensions in lifespan, the first robust evidence for the…
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