grant
Magnetoelastic Vascular Grafts
Organization UNIVERSITY OF CALIFORNIA LOS ANGELESLocation LOS ANGELES, UNITED STATESPosted 1 Sept 2025Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY2025AI AugmentedAI assistedAI drivenAI enhancedAI integratedAI model trainingAI poweredAI systemAI trainingAddressAffectAngiogramAngiographyAortocoronary BypassArtificial IntelligenceArtificial Intelligence enhancedArtificial OrgansArtificial intelligence model trainingAugmented by AIAugmented by the AIAugmented with AIAugmented with the AIAutograftAutologous TransplantationAutotransplantBig DataBigDataBiologicalBiological MonitoringBlood DiseasesBlood VesselsBlood flowBrain VascularBypassCardiovascularCardiovascular Body SystemCardiovascular Organ SystemCardiovascular systemCell Communication and SignalingCell SignalingChronicClinicalCollaborationsCommon Rat StrainsCommunitiesComplicationComputer ReasoningContrast AgentContrast DrugsContrast MediaCoronary Artery BypassCoronary Artery Bypass GraftingCoronary Artery Bypass SurgeryCoronary arterial bypassData AnalysesData AnalysisDependenceDevelopmentDiagnosisDiameterDiseaseDisease ManagementDisorderDisorder ManagementDoctor of MedicineDoctor of PhilosophyDoppler UltrasoundElectronsEndotheliumEquipmentEvaluationExposure toFamily suidaeGoalsHeart VascularHematologic DiseasesHematological DiseaseHematological DisorderHematologyHemodialysesHemodialysisHeterograftHeterologous TransplantationHigh PrevalenceHistologyHumanHuman FigureHuman bodyImmune Cell ActivationIncidenceInterventionIntracellular Communication and SignalingIonizing Electromagnetic RadiationIonizing radiationLength of LifeLifeLongevityLongitudinal StudiesM.D.MR ImagingMR TomographyMRIMRIsMachine IntelligenceMagnetic Resonance ImagingMedicalMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMicrosurgeryMinorModelingModern ManMonitorNMR ImagingNMR TomographyNatureNegative Beta ParticleNegatronsNuclear Magnetic Resonance ImagingOperative ProceduresOperative Surgical ProceduresPathological ConstrictionPeripheralPh.D.PhDPigsPlayPostoperativePostoperative ComplicationsPostoperative PeriodProceduresQOLQOL improvementQuality of lifeR-Series Research ProjectsR01 MechanismR01 ProgramRadiation-Ionizing TotalRadiopaque MediaRatRats MammalsRattusReoperationRepeat SurgeryResearchResearch GrantsResearch Project GrantsResearch ProjectsResearch ResourcesResourcesRoentgen RaysRoleSignal TransductionSignal Transduction SystemsSignalingStenosisSuidaeSurgeonSurgicalSurgical InterventionsSurgical ProcedureSwineSystemTestingTimeTime ManagementTranslatingTranslational ResearchTranslational ScienceTransmissionVascular DiseasesVascular DisorderVascular GraftX-RadiationX-Ray RadiationX-rayXenograftXenograft procedureXenotransplantationXrayZeugmatographyangiographic imagingartificial intelligence assistedartificial intelligence augmentedartificial intelligence drivenartificial intelligence integratedartificial intelligence poweredartificial intelligence trainingautologous graftautotransplantationbiocompatibilitybioelectronicsbiologicbiological signal transductionbiomaterial compatibilitybiomonitoringblood disorderblood vessel disordercerebral vascularcerebro-vascularcerebrovascularcirculatory systemclinical translationclinical validationclinically translatablecontinuous monitoringcoronary bypasscost effectivedata interpretationdesigndesigningdevelopmentalempowermentengineered vascular tissueengineered vascularized tissueenhanced with AIenhanced with Artificial Intelligenceexperiencefemoral arteryhemodynamicsimage-based methodimaging methodimaging modalityimmune activationimplantationimprovedimprovements in QOLimprovements in quality of lifein vivoin vivo Modelinnovateinnovationinnovativeionizing outputlong-term studylongitudinal outcome studiesmultidisciplinarynovelpig modelpiglet modelporcineporcine modelpost-operative complicationsprosthetic organsquality of life improvementreconstructionrepairrepairedresponsesocial rolestemsuidsurgeryswine modeltechnology platformtechnology systemtranslation researchtranslational investigationtransmission processvascularvascular dysfunctionvascular tissue engineeringvasculopathywearablewearable devicewearable electronicswearable systemwearable technologywearable toolwearableswirelesswireless transmissionxeno-transplantxeno-transplantation
Description preview
PROJECT SUMMARY
Vascular grafts, which are used to replace, bypass, or repair diseased blood vessels in approximately 3 million
surgeries each year, play a crucial role in various medical procedures. However, stenosis remains a significant
issue of post-implantation, with nearly 40% of grafts experiencing reduced patency within 2 years. This high…
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