grant
Long-term Trajectory of SSRI-Induced Height Growth Suppression
Organization BAYLOR COLLEGE OF MEDICINELocation HOUSTON, UNITED STATESPosted 1 Sept 2024Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY20250-11 years old12-20 years old17 year old17 years of age19 year old19 years of age20 year old20 years of age21+ years old5-HT5-Hydroxytryptamine5HTActive Follow-upAddressAdolescenceAdolescentAdolescent YouthAdultAdult HumanAdverse ExperienceAdverse eventAffectAgeAnxiety DisordersBMIBMI percentileBMI z-scoreBlood SerumBody mass indexBronchial-Dilating AgentsBronchodilator AgentsBronchodilatorsChildChild YouthChildhoodChildren (0-21)ChronicCitalopramClinicalClinical TrialsCognitiveCommon Rat StrainsCytalopramDataDepressive SyndromesDepressive disorderDevelopmentDoseDrug PrescribingDrug PrescriptionsDrugsDysfunctionEnrollmentEnteramineEpiphyseal PlateEpiphysial cartilageEscitalopramFailureFemaleFemurFluoxetinFluoxetineFunctional disorderFunding OpportunitiesGeneralized GrowthGrowthGrowth AgentsGrowth FactorGrowth HormoneGrowth Hormone 1Growth PlateGrowth SubstancesHeightHippophaineHormone secretionHumulin RInsulinInvestigationLightMajor Depressive DisorderMedicationMetabolicNovolin RObesityParticipantPharmaceutical PreparationsPhotoradiationPhysiopathologyPituitary Growth HormonePredispositionPrevalenceProteins Growth FactorsProzacPsychotherapyPubertyQuetelet indexRatRats MammalsRattusRegular InsulinReportingResearchRisk FactorsRisk ReductionSSRISSRIsSamplingSelective Serotonin Reuptake InhibitorSelective serotonin re-uptake inhibitorSerotoninSertralineSerumSomatotropinStagingSusceptibilityTimeTissue GrowthWorkWritingYouthYouth 10-21Zoloftactive followupadiposityadolescence (12-20)adulthoodage 17 yearsage 19 yearsage 20 yearsage groupagesanti-depressant agentanti-depressant drugsanti-depressantsanti-depressive agentsbone ageboysclinical decision-makingclinical depressionclinical predictorsclinical significanceclinically significantcorpulencedevelopmentaldrug/agentenrollevidence basefollow upfollow-upfollowed upfollowupgirlshormonal secretionhormonal signalshormone signalsinhibitor druginhibitor therapeuticinhibitor therapyjuvenilejuvenile humankidslong-term sequelaelumen dilatormajor depressionmajor depression disordermalemedication prescriptionnineteen year oldnineteen years oldontogenypathophysiologypediatricpre-clinicalpreclinicalprescribed medicationpsychologicpsychologicalpsychostimulantreduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskrisk-reducingserotonin reuptake inhibitorseventeen year oldseventeen years of agesexside effectsomatotropic hormonetwenty year oldtwenty years of ageyoungsteryouth age♀♂
Description preview
PROJECT SUMMARY
Adolescence is most strikingly characterized by the pubertal growth spurt. It is also a time when the
prevalence of depressive and anxiety disorders increases dramatically, a fact reflected in the widespread use of
antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs). In fact, antidepressants comprise
the…
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