grant

Long-term effects of electronic cigarettes on brain health

Organization WAKE FOREST UNIVERSITY HEALTH SCIENCESLocation WINSTON-SALEM, UNITED STATESPosted 1 Jul 2025Deadline 31 Mar 2030
NIHUS FederalResearch GrantFY202521+ years oldAHRRAbstinenceAdolescent and Young AdultAdultAdult HumanAffectBiological MarkersBrainBrain Nervous SystemCP11CY11CYP1A1CYP1A1 geneCerebrovascular CirculationChronicCigaretteCross Sectional AnalysisCross-Sectional AnalysesCross-Sectional StudiesCross-Sectional SurveyDNA MethylationDiseaseDisease Frequency SurveysDisorderElectronic cigaretteEncephalonEnvironmental FactorEnvironmental Risk FactorForcepHealthInflammationKnowledgeLong-Term EffectsMarketingMeasuresMethylationNicotineOutcomeOxidative StressP1-450P450-CP450DXP450D\XPathologyPatternPhysiologicPhysiologicalPoliciesPopulationPrefrontal CortexRecommendationRecoveryReportingReproducibilityResearchSafetySiteSmokerSmokingSmoking HistoryStructureTestingTimeadulthoodbio-markersbiologic markerbiomarkerblood flow in brainbrain blood circulationbrain blood flowbrain healthcease smokingcerebral blood flowcerebral circulationcerebrocirculationcerebrovascular blood flowcigarette smokecigarette smoke exposurecognitive performancecombustible cigaretteconventional cigarettee-cige-cig aerosolse-cig usee-cig vapore-cigarettee-cigarette aerosolse-cigarette usee-cigarette vaporecigecig aerosolsecig useecig vaporecigaretteecigarette aerosolsecigarette useecigarette vaporelectronic cigarette aerosolelectronic cigarette useelectronic cigarette vaporenvironmental riskex-smokerexposure to cigarette smokeformer smokergenome scalegenome-widegenomewidegray matterimprovedmethylation patternnever smokernicotine consumptionnicotine usenon-smokernonsmokerpack/yearpublic health relevancequit smokingresponsesmoking cessationstop smokingsubstantia albasubstantia griseatraditional cigarettewhite matter
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Description preview

ABSTRACT
Electronic cigarettes (e-cigs) are being touted as safer alternatives to traditional cigarettes, which have well-

known harmful effects on the brain due to combustion-related inflammation and oxidative stress. Some

smokers report using e-cigs to help quit smoking and switch to exclusive e-cig use. However, nicotine itself, as

well as the…

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Long-term effects of electronic cigarettes on brain health — WAKE FOREST UNIVERSITY HEALTH SCIENCES | UNITED STATES | Ju | Dev Procure