grant
Long-range inhibitory neuron circuit organization and cortical function
Organization ALBERT EINSTEIN COLLEGE OF MEDICINELocation BRONX, UNITED STATESPosted 1 Mar 2023Deadline 29 Feb 2028
NIHUS FederalResearch GrantFY2026ASDAffectAnimalsAreaArousalAutismAutistic DisorderAxonBNOSBehavioralBrainBrain Nervous SystemBrain imagingBrain regionCell BodyCellsCerebrumCognitionCommunicationCyclic SomatostatinDataDelta WaveDelta Wave sleepDiseaseDisorderDistantEEGEarly Infantile AutismElectroencephalogramElectroencephalographyEncephalonFrequenciesGene ExpressionGenerationsGeneticGrowth Hormone Inhibiting FactorsGrowth Hormone-Inhibiting HormoneHealthHumanInfantile AutismKanner's SyndromeKnowledgeLinkMeasuresMental DepressionMental disordersMental health disordersMiceMice MammalsMinorityMissionModern ManMonitorMorphologyMurineMusNC-NOSNNOSNOS 1 proteinNOS type INOS1 proteinNational Institutes of HealthNeocortexNerve CellsNerve UnitNervous System DiseasesNervous System DisorderNeural CellNeural Constitutive Nitric Oxide SynthaseNeurocyteNeurologic DisordersNeurological DisordersNeuronsNitric Oxide Synthase Type IOutputPatternPerceptionPlayPositionPositioning AttributePrimary visual cortexPsychiatric DiseasePsychiatric DisorderPublic HealthPyramidal CellsRabies mappingRabies trans synaptic tracingRabies virus mediated mappingReptilesReptiliaResearchRestRoleSRIHSRIH-14SchizophreniaSchizophrenic DisordersSensorySleepSlow-Wave SleepSomatostatinSomatostatin-14Somatotropin Release Inhibiting FactorsSomatotropin Release-Inhibiting HormoneStimulusStriate CortexStriate areaTestingUnited States National Institutes of HealthVisualVisual PerceptionVisual SystemVisualizationWakefulnessWorkarea striataautism spectral disorderautism spectrum disorderautistic spectrum disorderbrain nitric oxide synthasebrain visualizationcell typecerebraldementia praecoxdepressiondiscrimination taskextracellulargrowth hormone release inhibiting factorhomotypical corteximage-based methodimaging methodimaging modalityin vivoinhibitory neuroninsightisocortexmental illnessmillimeternNOS enzymeneocorticalneopalliumneurological diseaseneuronalneuronal NOSneuronal circuitneuronal circuitryneuronal form of nitric oxide synthaseneuronal nitric oxide synthaseneuropsychiatric diseaseneuropsychiatric disordernitric oxide synthase 1noveloperationoperationsoptogeneticspostsynapticpreservationpresynapticpsychiatric illnesspsychological disorderrabies based mappingrabies based retrograde mappingrabies circuit tracingrabies mediated retrograde monosynaptic tracingrabies retrograde tracingrabies tracerrabies tracingrabies viral tracingrabies virus mediated circuit mappingrabies virus monosynaptic circuit tracingrabies virus monosynaptic tracingrabies virus neurotracerrabies virus retrograde tracingrabies virus tracingresponseschizophrenicsocial roletheoriestooltracing with rabiesvisual discrimination
Description preview
Project Summary
Cortical activity is highly dependent on behavioral state of an animal with different states, such as sleep and
wake, having profound impact on cognition and cortical processing. At the brain level, behavioral states (such
as sleep and wakefulness) are associated with distinct patterns of cortical activity (or cortical states),…
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