grant

Local and Long-Range Cortical Circuits Underlying Tactile Perception

Organization BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)Location BOSTON, UNITED STATESPosted 1 Dec 2024Deadline 30 Nov 2029
NIHUS FederalResearch GrantFY20262-photon2-photon microscopyAddressAnatomic SitesAnatomic structuresAnatomyArchitectureAreaAssayBehaviorBehavioralBindingBioassayBiological AssayBrainBrain Nervous SystemCalciumCategoriesCell Communication and SignalingCell SignalingCommunicationComputer ModelsComputerized ModelsDecision MakingDissectionDorsalElectron MicroscopyEncephalonEngineering / ArchitectureEnvironmentGenerationsGoalsImageIntracellular Communication and SignalingLabelMeasuresMediatingMemoryMiceMice MammalsModelingMolecularMolecular InteractionMotionMotorMotor CortexMurineMusNeocortexNerve CellsNerve UnitNervous System DiseasesNervous System DisorderNeural CellNeuranatomiesNeuranatomyNeuroanatomiesNeuroanatomyNeurocyteNeurologic DisordersNeurological DisordersNeuronsPathway interactionsPerceptionPlayPopulationPopulation DynamicsPositionPositioning AttributeProcessResolutionRoleRouteSamplingSchemeSensorySignal TransductionSignal Transduction SystemsSignalingSomatosensory CortexStimulusSynapsesSynapticSystemTactileTestingTheoretic ModelsTheoretical modelTimeVibrissaeVirusWhiskersWorkbarrel cortexbiological signal transductioncell typecognitive functioncomputational modelingcomputational modelscomputer based modelscomputerized modelingexcitatory neuronflexibilityflexiblehomotypical corteximagingin vivo two-photon imaginginformation processinginsightisocortexneopalliumnetwork architectureneuralneurological diseaseneuronalpathwayreconstructionresolutionsresponsesensory integrationsocial rolesomatosensorysomesthetic sensory cortexspatial RNA sequencingspatial gene expression analysisspatial gene expression profilingspatial resolved transcriptome sequencingspatial transcriptome analysisspatial transcriptome profilingspatial transcriptome sequencingspatial transcriptomicsspatially resolved transcriptomicsspatio transcriptomicssynapsetooltwo photon excitation microscopytwo photon microscopytwo-photon
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PROJECT SUMMARY
Perception can only fully be understood in the context of behavior. Stimulus feature binding, sensorimotor

integration, and information routing are each an aspect of sensory processing that is dynamically engaged on a

moment-to-moment basis depending on behavioral demands. Deficits in each of these aspects of perception are…

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Local and Long-Range Cortical Circuits Underlying Tactile Perception — BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) | UNITED | Dev Procure