grant

LIQUID CHROMATOGRAPHY WITH TANDEM MASS SPECTROMETRY (HPLC-MS-MS) ASSAY VALIDATION AND SAMPLE TESTING

Organization BATTELLE CENTERS/PUB HLTH RES & EVALUATNLocation COLUMBUS, UNITED STATESPosted 16 Jun 2023Deadline 15 Jun 2028
NIHUS FederalResearch GrantFY2023AgonistAssayBioassayBiologic AssaysBiologic ProductsBiological AgentBiological AssayBiological ProductsBladderBladder Urinary SystemClinical TrialsCooperative AgreementsDevelopmentDiabetes MellitusDisseminated SclerosisDrugsEvaluationFundingGoalsHPLCHigh Performance Liquid ChromatographyHigh Pressure Liquid ChromatographyHigh Speed Liquid ChromatographyIn VitroIncontinenceIndividualIntestinalIntestinesInvestigational DrugsInvestigational New DrugsInvoluntary MuscleLeadLiquid ChromatographyMedicationMultiple SclerosisNINDSNK2NKANKNANational Institute of Neurological Diseases and StrokeNational Institute of Neurological Disorders and StrokePb elementPeptidesPharmaceutic PreparationsPharmaceutical PreparationsReceptor ProteinSamplingSmooth MuscleSpinal InjuriesTAC1TAC1 geneTAC2TestingU-Series Cooperative AgreementsValidationVisceralbiologicsbiopharmaceuticalbiotherapeutic agentbowelclinical candidatedevelopmentaldiabetesdrug/agentheavy metal Pbheavy metal leadin vivoinsular sclerosislead optimizationmanufacturepre-clinical studypreclinical studyreceptorspine injurytandem mass spectrometrytherapeutic candidateurinary bladdervalidationsvertebral injury
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Description preview

The NINDS, via its BPN-Biologics network, is currently funding a cooperative agreement for the development of a neurokinin2 receptor (NK2R) agonist peptide that is a smooth muscle inotropic drug for restoring bladder and bowel control for individuals with spinal injury, multiple sclerosis, or diabetes. The goals of the BPN-Biologics cooperative…

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