grant
Irradiator Shared Resource
NIHUS FederalResearch GrantFY2025Animal Experimental UseAnimal ExperimentationAnimal ResearchAnimalsAntitumor ResponseBasic ResearchBasic ScienceBiologicalCCSGCancer CenterCancer Center Support GrantCancersCapitalCell BodyCell Communication and SignalingCell Culture TechniquesCell SignalingCellsCesiumChemicalsCollimationCollimatorConsultationsControlled EnvironmentCs elementDNADNA mutationDeoxyribonucleic AcidDose RateEnsureEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessExperimental DesignsFundingGamma RadiationGamma RaysGeneticGenetic ChangeGenetic defectGenetic mutationGenomicsHumanImmune responseImmunosuppressionImmunosuppression EffectImmunosuppressive EffectIndividualInduction of ApoptosisIntracellular Communication and SignalingInvestigatorsIonizing Electromagnetic RadiationIonizing radiationLesionMaintenanceMalignant NeoplasmsMalignant TumorMiceMice MammalsModern ManMolecularMurineMusMutationNamesPathway interactionsPhysiciansPrincipal InvestigatorRadiationRadiation BiologyRadiation PhysicsRadiation induced damageRadiation-Ionizing TotalRadiobiologyRecommendationResearchResearch PersonnelResearch ResourcesResearchersResource SharingResourcesRoentgen RaysSamplingScientistServicesSignal TransductionSignal Transduction SystemsSignalingSpleenSpleen Reticuloendothelial SystemTechnologyTrainingTransgenic AnimalsTumor CellUniversitiesX-RadiationX-Ray RadiationX-rayXrayYale Cancer Centeranimal experimentationsanti-cancer researchanti-tumor responseartificial environmentbiologicbiological effect of radiationbiological signal transductioncancer immunologycancer researchcell culturecell culturesconsultationcostcost effectivedesigndesigningepigeneticallyexperimentexperimental researchexperimental studyexperimentsgenome integritygenome mutationgenomic integrityhost responseimage guidanceimage guidedimmune suppressionimmune suppressive activityimmune suppressive functionimmune system responseimmunoresponseimmunosuppressive activityimmunosuppressive functionimmunosuppressive responseimprovedionizationionizing outputirradiationmalignancymembernamenamednamingneoplasm immunologyneoplasm/cancerneoplastic cellpathwayprogramsquality assuranceradiation damageradiation effectrepairrepairedresearch studytooltumor immunologyγ-Radiationγ-Ray
Description preview
IRRADIATOR SHARED RESOURCE – PROJECT SUMMARY/ABSTRACT
The Irradiator Shared Resource (ISR), formerly known as the Cesium-137 Irradiator Shared Resource, was
established in 1991 with a Cesium-137 gamma-ray irradiator to provide accurate, cost-effective, convenient, and
reliable access to ionizing radiation to Yale University investigators for…
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