grant

iPRISM (Imaging-enhanced Prediction of RIsk for Sudden cardiac death in hcM)

Organization OREGON HEALTH & SCIENCE UNIVERSITYLocation PORTLAND, UNITED STATESPosted 15 Aug 2025Deadline 31 May 2029
NIHUS FederalResearch GrantFY20250-11 years old21+ years oldAI AugmentedAI assistedAI drivenAI enhancedAI integratedAI poweredAI systemAdolescentAdolescent YouthAdultAdult HumanAdverse effectsAmericanAppearanceArrhythmiaArtificial IntelligenceArtificial Intelligence enhancedAsymmetric Septal HypertrophyAugmented by AIAugmented by the AIAugmented with AIAugmented with the AICardiacCardiac ArrhythmiaCell Communication and SignalingCell SignalingCessation of lifeChildChild YouthChildhoodChildren (0-21)CicatrixCirculatory CollapseClinical ManagementCollaborationsComputer ReasoningDangerousnessDeathDedicationsDefibrillatorsDevelopmentECGEKGEchocardiogramEchocardiographyElectric Shock Cardiac StimulatorsElectrocardiogramElectrocardiographyElectrophysiologyElectrophysiology (science)ElementsEventGadoliniumGd elementGeneticGenetic DiseasesGenotypeHeartHeart ArrhythmiasHereditaryHereditary ventricular hypertrophyHeterogeneityHistoryHumanHypertrophic CardiomyopathyHypertrophic Obstructive CardiomyopathyIdiopathic Hypertrophic Subvalvular StenosisIdiopathic hypertrophic subaortic stenosisImageImage AnalysesImage AnalysisImage EnhancementImplantImplantable Cardioverter-DefibrillatorsImplantable DefibrillatorsInheritedIntracellular Communication and SignalingLifeMR ImagingMR TomographyMRIMRI ScansMRIsMachine IntelligenceMagnetic ResonanceMagnetic Resonance ImagingMagnetic Resonance Imaging ScanManualsMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMethodsModelingModern ManMorbidityMorbidity - disease rateMyocardialMyocardiumNMR ImagingNMR TomographyNeurophysiology / ElectrophysiologyNuclear Magnetic Resonance ImagingOperative ProceduresOperative Surgical ProceduresOutcome StudyPatient riskPatientsPhysiciansPredicting RiskPrevalencePrincipal Component AnalysesPrincipal Component AnalysisRecording of previous eventsRiskRisk AssessmentRisk FactorsRoleScarsShockSignal TransductionSignal Transduction SystemsSignalingSiteStimulators, Electrical, Cardiac, ShockSurgicalSurgical InterventionsSurgical ProcedureTechniquesTestingTrainingTransthoracic EchocardiographyVentricular FibrillationWorkYouthYouth 10-21Zeugmatographyadulthoodartificial intelligence assistedartificial intelligence augmentedartificial intelligence drivenartificial intelligence integratedartificial intelligence poweredartificial neural netartificial neural networkbiological signal transductioncardiac MRIcardiac functioncardiac magnetic resonance imagingcardiac musclechild patientscirculatory shockcohortcomputational neural networkdeath riskdevelopmentalelectrophysiologicalenhanced with AIenhanced with Artificial Intelligenceexperienceforecasting riskfunction of the heartgene testinggene-based testinggenetic conditiongenetic disordergenetic testingheart functionheart muscleheart sonographyhigh riskhistorieshypertrophic myocardiopathyimage evaluationimage interpretationimagingimaging biomarkerimaging markerimaging-based biological markerimaging-based biomarkerimaging-based markerimprovedimproved outcomeinnovateinnovationinnovativejuvenilejuvenile humankidsmortality risknew markernovelnovel biomarkernovel markeroutcome predictionpediatricpediatric patientspredict riskpredict riskspredicted riskpredicted riskspredicting riskspredictive riskpredicts riskpreventpreventingprognosticradiomicsrisk predictionrisk prediction systemrisk prediction toolrisk predictionsrisk stratificationshocksside effectsocial rolestatisticsstratify risksudden cardiac deathsurgerysynthetic neural networktoolyoungsteryouth age
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Project Summary
Hypertrophic cardiomyopathy (HCM) is an inherited heart condition where the heart is thicker than normal. It is

an inheritable genetic condition and the most common cause of sudden collapse and death (SCD) in children.

SCD can be prevented by placing an internal defibrillator (ICD) which can stop life-threatening arrhythmias by…

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