Investigating the vulnerability of hippocampal neurons to alpha synuclein oligomers
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Alpha-synuclein (alpha-syn) is a synaptic protein involved in key neuronal processes such as vesicle release and receptor trafficking. Recent evidence suggests that alpha-syn plays a role in age-related cognitive decline, particularly through its effects in the hippocampus. The CA2/3 region appears especially vulnerable, with alpha-syn aggregates…
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