Investigating the Role of Class-Switching on Oncogenic B Cell Receptor Signalling in Lymphoma
Description preview
Diffuse large B cell lymphoma (DLBCL) is the most common non-Hodgkin B cell lymphoma. It is an aggressive cancer that exhibits significant phenotypic and genetic heterogeneity. B cell receptor (BCR) signalling is a key driver of lymphoma growth and survival. However, therapies that target BCR signalling pathway only work in a subset of lymphoma…
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